肾透明细胞癌合并多发性骨髓瘤1例并文献复习

Renal clear cell carcinoma complicated with multiple myeloma:A case report and literature review

目的探讨肾癌骨转移同时合并多发性骨髓瘤的鉴别诊断及经验分享。方法回顾河北医科大学第三医院收治的肾透明细胞癌合并多发性骨髓瘤1例,并复习相关文献。结果患者中年男性,肾癌病史3年。因“背部疼痛”就诊,系统检查后取椎体肿物病理活检发现肾癌骨转移合并多发性骨髓瘤。结论提高临床医生对这两种恶性肿瘤合并存在的认识,尤其是当肾细胞癌患者出现新的溶解性骨病变时,通过全面检查鉴别骨转移与多发性骨髓瘤。

Objective To explore the differential diagnosis of kidney cancer with bone metastasis combined with multiple myeloma and to share experience.Methods A case of renal clear cell carcinoma combined with multiple myeloma admitted to the Third Hospital of Hebei Medical University was retrospectively analyzed,and the related literature was reviewed.Results The middle-aged male had the history of renal cancer with 3 years.The patient was treated for“back pain”,and pathological biopsy of vertebral mass after systematic examination revealed that the patient had kidney cancer with bone metastasis complicated with multiple myeloma.Conclusion Clinicians should improve the understanding of the coexistence of these two malignant tumors,especially when new osteolytic lesions are present in patients with renal cell carcinoma,a comprehensive examination is conducted to distinguish bone metastasis and multiple myeloma.