耳石症患者眩晕障碍及前庭症状运用倍他司汀联合Epley手法复位的影响研究

A Study of The Effect of Betahistine Combined with Epley Maneuver on Vertigo Disorders and Vestibular Symptoms in Patients with Benign Paroxysmal Positional Vertigo

目的针对耳石症患者眩晕障碍及前庭症状,探讨研究运用倍他司汀联合Epley手法复位的影响。方法整理2021年1月—2024年5月解放军总医院第八医学中心收治的90例耳石症患者的病历资料,患者存在眩晕障碍及前庭症状,并经眼球震颤试验、复杂前庭反射试验确诊,按随机数表法原则分为对照组(倍他司汀治疗)与观察组(倍他司汀联合Epley手法复位治疗),每组45例。对比两组治疗前后的眩晕障碍和平衡能力评分、治疗后的前庭症状评分、临床疗效。结果治疗前,两组眩晕障碍和平衡能力评分比较,差异无统计学意义(P>0.05);治疗后,两组眩晕障碍评分均下降、平衡能力评分均提升,但观察组眩晕障碍评分较对照组更低、平衡能力评分较对照组更高,差异有统计学意义(P<0.05)。治疗后,观察组头晕、恶心、头痛、眩晕、平衡、视觉敏感6项前庭症状评分均低于对照组,差异有统计学意义(P<0.05)。观察组临床疗效高于对照组,差异有统计学意义(P<0.05)。结论针对耳石症患者眩晕障碍及前庭症状,运用倍他司汀联合Epley手法复位可改善眩晕障碍,减轻前庭症状,提升平衡能力,取得更好疗效。

Objective This study aimed to investigate the effect of combining betahistine with Epley maneuver on vertigo disability and vestibular symptoms in patients with otolithiasis.Methods The information of 90 patients with otolithiasis was collated,all of which were indirectly diagnosed by the Eighth Medical Center of the PLA General Hospital from January 2021 to May 2024.All patients presented with vertigo disability and vestibular symptoms and were confirmed through nystagmus test and complex vestibular reflex test.The patients were randomly divided into a control group(treated with betahistine)and an observation group(treated with betahistine combined with Epley maneuver)based on the principle of random number table.The vertigo disability and balance ability scores before and after treatment,vestibular symptom scores after treatment,and clinical efficacy were collected and compared between the two groups.Results Before treatment,the vertigo disorder and balance ability scores of the two groups were comparable at baseline,and after treatment,the dizziness handicap scores in both groups decreased,and the balance ability scores increased simultaneously,but after treatment,the dizziness handicap scores in the observation group were lower than those in the control group,and the balance ability scores were higher than those in the control group(P<0.05).After treatment,the scores of six vestibular symptoms of dizziness,nausea,headache,vertigo,balance and visual sensitivity in the observation group were observably lower than the scores of six vestibular symptoms in the control group(P<0.05).The clinical efficacy rate in the observation group(95.56%)was higher than that in the control group(P<0.05).Conclusion For vertigo disorder and vestibular symptoms in patients with otolithiasis,betahistine combined with Epley maneuver reduction can improve vertigo disorder,alleviate vestibular symptoms,improve balance ability,and achieve better efficacy.