摘要
蝎毒多肽是由蝎尾节毒囊分泌产生的一类生物活性物质,其具有抗肿瘤、镇痛、抗菌、抗癫痫、抗惊厥等多种生理功能,发展前景广阔,已经成为当今生物医学领域研究热点。对蝎毒多肽的来源、分类、主要药理活性以及目前研究存在的问题进行系统综述,并对蝎毒多肽研究的未来发展方向进行展望,为蝎毒多肽的深度开发利用提供理论依据。参考文献74篇。
Scorpion venom peptides are bioactive substances secreted from the venom glands in the telson of scorpions,with a variety of physiological functions,including anti-tumor,analgesic,antibacterial,anti-epileptic,and anticonvulsant activities,making them highly promising for future development.Consequently,they have become a focal point of research in the field of biomedicine.This paper provides a systematic review of the sources,classification,and primary pharmacological activities of scorpion venom peptides,as well as the current research challenges.Furthermore,it discusses potential future directions for research,offering a theoretical foundation for the advanced development and utilization of scorpion venom peptides.Seventy-four references were quoted.
作者
宁淑博
邵新
冉志芳
刘雪
滕佳林
NING Shubo;SHAO Xin;RAN Zhifang;LIU Xue;TENG Jialin(Shandong University of Traditional Chinese Medicine,Jinan 250355,China;Shandong Academy of Chinese Medicine,Jinan 250013,China)
出处
《山东中医杂志》
2024年第11期1301-1308,共8页
Shandong Journal of Traditional Chinese Medicine
关键词
全蝎
蝎毒多肽
抗肿瘤
镇痛
抗菌
抗癫痫
抗惊厥
抗血栓
scorpion
scorpion venom polypeptide
anti-tumor
analgesic
antibacterial
anti-epileptic
anticonvulsant