血液透析联合解毒泄浊方治疗慢性肾功能衰竭的临床效果分析

Clinical Effect Research of Hemodialysis Combined with Detoxification and Turbidity Relief Prescription in Treatment of Chronic Renal Failure

目的分析临床上血液透析联合解毒泄浊方治疗慢性肾功能衰竭的效果。方法选择2022年1月—2023年3月本院收治的120例慢性肾功能衰竭患者为研究对象,随机将其分为观察组和对照组,每组60例。对照组接受血液透析治疗,观察组在对照组的基础上进行解毒泄浊方治疗。3个月后观察两组患者的临床效果、炎症因子及肾功能指标改善情况。结果观察组治疗有效率高于对照组(P<0.05)。治疗后,观察组各项炎症因子(IL-6、CRP、TNF-ɑ)水平均明显低于对照组(P<0.05);观察组Cr、BUN水平明显低于对照组,CCR水平明显高于对照组(P<0.05)。结论血液透析联合解毒泄浊方治疗慢性肾功能衰竭效果显著,安全可靠,值得推广使用。

Objective To summarize and analyze clinical effect of hemodialysis combined with detoxification and turbidity relief prescription in treatment of chronic renal failure.Methods The paper chose 120 patients with chronic renal failure in our hospital from January 2022 to March 2023 as research and analysis subjects,and divided them into groups randomly before treatment with informed consent of patients and their families,with 60 cases in each group,treated with hemodialysis treatment,and observation group was treated with continuous treatment with detoxification and turbidity relief prescription.After 3 months,clinical effect,improvement of inflammatory factors and renal function indicators,and adverse reactions were observed between two groups.Results①Effective rate of treatment in observation group was 81.67%,higher than control group,with significant difference(P<0.05).②After treatment,levels of various inflammatory factors(IL-6,CRP and TNF-α)were significantly lower than control group,with significant difference(P<0.05).③After treatment,Cr(152.2±6.9)μmol/L,BUN(12.5±0.8)mmol/L in observation group was significantly lower than control group,CCR(50.1±0.8)ml/min was significantly higher than control group,with significant difference(P<0.05).Conclusion Combination of hemodialysis and detoxification and turbidity relief prescription can achieve significant effect for chronic renal failure,which is safe and reliable,and is worthy of promotion and application.