布地奈德雾化吸入治疗毛细支气管炎感染后喘息的效果分析

Application Value Research of Budesonide Nebulization Inhalation in Treatment of Asthma after Bronchiolitis Infection

目的分析在毛细支气管炎感染后喘息治疗中用布地奈德吸入的效果。方法选取2021年1月—2023年1月本院收治的90例毛细支气管炎感染发生后出现喘息的患者作为研究对象,以随机数字表法将其分为观察组(n=45)和对照组(n=45)。对照组采用常规治疗,观察组在常规治疗的基础上采用布地奈德吸入治疗,比较分析两组治疗后临床效果、临床症状改善时间(湿啰音、憋喘、咳嗽),并比较两组治疗前后肺功能(FVC、FEV1、FEV1/FVC)。结果治疗前,观察组与对照组肺功能比较,差异无统计学意义(P>0.05);治疗后,观察组肺功能指标值较对照组升高更明显(P<0.05)。观察组临床治疗效果较对照组更高,临床症状改善时间较对照组更短(P<0.05)。结论布地奈德在毛细支气管炎后喘息治疗中可提高疾病治疗效果,较常规治疗措施更能改善肺功能,缩短症状改善时间,疗效更显著,值得临床推广应用。

Objective To analyze application value of budesonide inhalation therapy in treatment of wheezing after bronchiolitis infection.Methods The paper chose 90 wheezing patients with bronchiolitis infection in our hospital from January 2021 to January 2023 as observation subjects,and divided them into two groups randomly with number table method.45 cases in observation group were treated with budesonide,while 45 cases in control group with routine treatment.Clinical effect and clinical symptoms improvement time(moist rales,wheezing,and coughing)were compared and analyzed,lung function(FVC,FEV1,FEV1/FVC)before and after treatment was statistically was compared between two groups.Results There was no statistically significant difference in lung function between observation group and control group before treatment(P>0.05).After treatment,observation group showed more significant increase in lung function than control group,with statistical significance,(P<0.05).Observation group had higher clinical effect and shorter clinical symptoms improvement time than control group,with statistical significance,(P<0.05).Conclusion Budesonide can improve curative effect of wheezing of patients with bronchiolitis,with better curative effect than routine treatment measures,can improve lung function,shorten symptom improvement time,which is worthy of clinical promotion and application.