非阿司匹林非甾体类抗炎药处方审核与实践

Prescription audit and practice of non-aspirin non-steroidal anti-inflammatory drugs

目的制定非阿司匹林非甾体类抗炎药处方的审核细则,借助信息化手段提升处方审核的有效性。方法基于诊疗指南、临床路径和专业文献,并结合临床用药经验从药物适应证、用法用量、给药途径、特殊人群、重复用药、药物禁忌6个方面梳理非阿司匹林非甾体类抗炎药的处方审核细则,并在临床药学实践中加以修订,利用信息化系统对处方问题进行分级别管理。结果制定非阿司匹林非甾体类抗炎药审核细则254条,并比较不同模式对不合理处方问题的筛查数据,其中常规模式筛查出1类问题共计16条,占比0.75%,制定规则后的审核模式筛查出6类问题,共计213条,占比9.03%,差异具有统计学意义(P<0.01)。结论药师利用信息化手段进行处方审核与实践,提升了处方审核的准确性和有效性,并发挥了药师的价值。

Objective To establish the rules for the prescription review of non-aspirin non-steroidal anti-inflammatory drugs,and to improve the effectiveness of prescription audit by means of information technology.Methods Based on diagnosis and treatment guidelines,clinical pathways and professional literature,and combined with clinical drug use experience,the prescription review rules of non-aspirin non-steroidal anti-inflammatory drugs were sorted out from six aspects of drug indications,usage and dosage,route of administration,special population,repeated drug use,and drug conscription,and revised in clinical pharmacy practice.Information system was used to conduct graded management of prescription problems.Results Formulate 254 prescription review rules of non-aspirin non-steroid anti-inflammatory drugs.The screening data of unreasonable problems in different modes were compared,among which 16 types of problems were detected in the conventional mode,accounting for 0.75%.After the rules,the audit mode screened 6 types of problems,a total of 213 problems,accounting for 9.03%,and the differences were statistically significant(P<0.01).Conclusion Pharmacists can Improve the efficiency of prescription audit and give full play to the value of pharmacists by use information technology.