基于数据挖掘技术探讨针刺治疗卒中后抑郁的选穴规律

Discussion on rules of acupoint selection for acupuncture treatment of post-stroke depression based on data mining

目的应用数据挖掘技术探讨针刺治疗卒中后抑郁的临床选穴规律。方法检索中国期刊全文数据库(CNKI)、万方(Wanfang)数据库2011年1月1日至2022年3月1日针刺治疗卒中后抑郁的临床研究文献,利用Excel建立针刺治疗卒中后抑郁处方选穴数据库,采用SPSS Modeler 18.0软件进行腧穴关联规则分析,采用SPSS 23.0软件进行聚类分析。结果共纳入文献114篇,涉及针灸处方114首,腧穴92个,腧穴使用总频次1075次,使用频次前七的依次为百会、内关、太冲、三阴交、神门、足三里、印堂;重用督脉、肝经及膀胱经穴位;头面颈部、下肢部、上肢部腧穴使用频率高于其他部位;最常用的腧穴组合为百会-内关、百会-太冲,且支持度最高;聚类分析共得出4个有效聚类和4个核心穴组。结论针刺治疗卒中后抑郁注重脏腑辨证选穴和上下配穴,多以通督醒脑、升发阳气、解郁安神、调畅气机为治则,疗效可靠。

Objective To investigate the clinical acupoint selection rules of acupuncture for treating post-stroke depression using data mining technology.Methods A search was conducted in the CNKI and Wanfang databases for clinical research literature on acupuncture treatment for post-stroke depression from January 1,2011 to March 1,2022.An Excel database of acupuncture prescriptions for post-stroke depression was established,and SPSS Modeler 18.0 software was used to analyze acupoint association rules,with cluster analysis performed using SPSS 23.0 software.Results A total of 114 literatures were included,comprising 114 acupuncture prescriptions,92 acupoints and 1075 instances of acupoint use.The top seven most frequently used acupoints are Baihui(DU20),Neiguan(PC6)-Taichong(LR3),Sanyinjiao(SP6),Shenmen(HT7)-Zusanli(ST36),and Yintang(EX-HN3);emphasis is placed on Du meridian points as well as liver and bladder meridian points;acupuncture treatments predominantly target the head,face,neck,lower extremities and upper extremities.The most common combinations include Baihui-Neiguan and Baihui-Taichong with high support degrees.Cluster analysis yielded four effective clusters and four key acupoint combinations.Conclusion Acupuncture treatment for post-stroke depression emphasizes differentiation of viscera points along with combining upper and lower points while adhering to therapeutic principles such as activating Du meridian and awakening the brain,elevating Yang qi,relieving depression,and calming the mind while regulating qi and energy.The therapeutic effect is reliable.