基于“活血化瘀理论”针刺联合汤剂辅助急性脑梗死患者溶栓治疗的临床疗效

Clinical Efficacy of Acupuncture Combined with Decoction As An Adjuvant Therapy for Thrombolytic Therapy in Acute Cerebral Infarction Based on“Promoting Blood Circulation to Remove Blood Stasis Theory”

目的探究基于“活血化瘀理论”针刺联合汤剂辅助急性脑梗死患者溶栓治疗的临床疗效。方法选取该院2018年1月—2022年1月收治的200例急性脑梗死患者为研究对象,采用随机数字表法分为观察组100例与对照组100例。对照组给予常规溶栓治疗,观察组在此基础上联合使用汤剂合“活血化瘀理论”针刺治疗。观察两组患者临床疗效与预后不良事件发生。结果观察组临床总有效率为93.00%(93/100),显著高于对照组82.00%(82/100)(χ^(2)=5.531,P=0.019)。观察组预后不良事件发生率为4.00%(4/100),略低于对照组7.00%(7/100),但两组预后不良事件发生率差异无统计学意义(χ^(2)=0.866,P=0.352)。结论基于“活血化瘀理论”针刺联合汤剂辅助能有效提高急性脑梗死患者临床疗效,降低炎症因子水平,改善氧化应激反应和提升患者临床生活质量。

Objective To investigate the clinical efficacy of acupuncture combined with decoction as an adjuvant therapy for thrombolytic therapy of acute cerebral infarction based on“promoting blood circulation to remove blood stasis theory”.Methods Two hundred patients with acute cerebral infraction in the hospital from January 2018 to January 2022 were enrolled,and assigned into two groups by random number table methods,each with 100 cases.The control group received routine thrombolytic therapy.Based on this,the observation group received decoction combined with acupuncture based on“promoting blood circulation to remove blood stasis theory”.Then the clinical efficacy and adverse events were observed in both groups.Results The overall efficacy rate was 93.00%(93/100)in the observation group,which was remarkably higher than 82.00%(82/100)in the control group(χ^(2)=5.531,P=0.019).The adverse events rate was 4.00%(4/100)in the observation group,which was slightly lower than 7.00%(7/100)in the control group,with no statistical difference(χ^(2)=0.866,P=0.352).Conclusion The application of acupuncture combined with decoction based on“promoting blood circulation to remove blood stasis theory”as adjuvant therapy for thrombolytic therapy in acute cerebral infarction can effectively attenuate the inflammation response,alleviate the oxidative stress response and improve the quality of life of patients.