俞募穴针刺法治疗慢性支气管炎急性发作期的效果评价

Effect Evaluation of Acupuncture at Shu and Mu Acupoints in Treatment of Acute Episode of Chronic Bronchitis

目的评价俞募穴针刺法治疗慢性支气管炎急性发作期的效果。方法选取2019年1月—2022年5月该院收治的68例慢性支气管炎急性发作期患者采用随机数字表法分为针刺组和西药组,各34例。西药组采用布地奈德治疗,在西药组的基础上,针刺组采用俞募穴针刺法治疗,两组均治疗2周。统计两组治疗2周后的临床疗效及临床症状消失时间,比较两组治疗前及治疗2周后炎症指标、肺功能及血气指标。结果治疗2周后,针刺组总有效率高于西药组(P<0.05)。针刺组各项临床症状消失时间短于西药组(P<0.05)。治疗2周后与治疗前比较,两组外周血中性粒细胞百分比、血清白细胞介素-17(IL-17)、细胞黏附分子-1(ICAM-1)、C反应蛋白(CRP)水平及二氧化碳分压(PaCO_(2))降低,针刺组低于西药组(P<0.05);两组呼气峰流速值(PEF)、用力肺活量(FVC)、1 s秒用力呼气量(FEV1)、氧分压(PaO_(2))、血氧饱和度(SpO_(2))升高,针刺组高于西药组(P<0.05)。结论俞募穴针刺法可有效改善慢性支气管炎急性发作期患者临床症状,降低机体炎症反应,改善其肺功能及血气指标,具有较好的治疗效果。

Objective To evaluate the effect of acupuncture at Shu and Mu acupoints on acute episode of chronic bronchitis.Methods From January 2019 to May 2022,68 patients with acute exacerbation of chronic bronchitis admitted to the hospital were randomly divided into the acupuncture group and the Western medicine group,with 34 cases in each group.The Western medicine group was treated with budesonide,while the acupuncture group was treated with acupuncture at Shu and Mu acupoints on the basis of the Western medicine group.Both groups were treated for 2 weeks.The clinical efficacy after 2 weeks of treatment and the disappearance time of clinical symptoms were statistically analyzed,and the inflammatory indexes,pulmonary function and blood gas indexes before and after 2 weeks of treatment were compared between the two groups.Results After 2 weeks of treatment,the total effective rate of the acupuncture group was higher than that of the Western medicine group(P<0.05).The disappearance time of cough,sputum,wheezing,pulmonary shadow and dyspnea in the acupuncture group were shorter than those in the Western medicine group(P<0.05).After 2 weeks of treatment,compared with those before treatment,the percentage of peripheral blood neutrophils,the levels of serum interleukin-17(IL-17),cell adhesion molecule-1(ICAM-1),C-reactive protein(CRP)and partial pressure of carbon dioxide(PaCO_(2))in the two groups decreased,which was lower in the acupuncture group than those in the Western medicine group(P<0.05).The values of peak expiratory flow rate(PEF),forced vital capacity(FVC),forced expiratory volume in 1 second(FEV1),partial pressure of oxygen(PaO_(2))and oxygen saturation(SpO_(2))of the two groups increased,which were higher in the acupuncture group than those in the Western medicine group(P<0.05).Conclusion The acupuncture at Shu and Mu acupoints could effectively improve the clinical symptoms of patients with acute exacerbation of chronic bronchitis,reduce the inflammatory response,improve the lung function and blood gas indexes,and had a good therapeutic effect.