2022年广东省高年级小学生HPV疫苗认知及接种意愿现状

HPV vaccine knowledge and willingness to vaccinate among senior primary school students in Guangdong province,2022:a cross-sectional survey

目的了解广东省高年级小学生人乳头状瘤病毒(HPV)疫苗的认知水平以及HPV疫苗接种意愿的影响因素,为政府部门制定推广策略提供参考依据。方法采用多阶段分层整群抽样方法,于2022年6—10月在广东省珠三角地区、东西两翼地区及粤北地区抽取7所小学5、6年级小学生1610人进行自填式问卷调查,分析高年级小学生对HPV、HPV疫苗的知晓率以及HPV疫苗的接种意愿及其影响因素。结果有效调查1314名小学生,HPV、HPV疫苗知识知晓率分别为61.49%和66.13%,接种意愿为74.73%。多因素logistic回归分析结果显示,女生(OR=2.15,95%CI=1.60~2.80)、城镇户籍(OR=1.56,95%CI=1.20~2.02)、珠三角地区(OR=3.64,95%CI=2.28~5.81)和粤北地区(OR=5.65,95%CI=4.00~7.97)的小学生更有可能听说过HPV;女生(OR=2.11,95%CI=1.60~2.78)、城镇户籍(OR=1.45,95%CI=1.11~1.89)、珠三角地区(OR=5.20,95%CI=3.06~8.83)和粤北地区(OR=6.30,95%CI=4.39~9.06)的小学生更有可能听说过HPV疫苗;女生(OR=7.07,95%CI=4.89~10.21)、听说过HPV(OR=1.94,95%CI=1.29~2.93)、知晓HPV疫苗(OR=1.65,95%CI=1.07~2.55)的小学生HPV疫苗接种意愿较高。结论广东省高年级小学生对HPV和HPV疫苗知识的知晓水平不高,但对HPV疫苗的接种意愿较高。户籍、居住地区、性别是影响高年级小学生群体HPV及HPV疫苗认知水平以及HPV疫苗接种意愿的主要因素。

Objective To investigate the knowledge and influencing factors of willingness to receive human papillomavirus(HPV)vaccination among senior primary school students in Guangdong province,and to provide a reference for relevant departments to formulate policies.Methods Using stratified multistage cluster sampling and a selfdeveloped questionnaire,1610 students in grades 5 and 6 from 7 primary schools in the Pearl River Delta region,eastern,western,and northern regions of Guangdong province were selected to participate in a self-administered,on-site,anonymous survey from June to October 2022.The students′awareness of HPV,knowledge of HPV vaccination,willingness to receive HPV vaccination,and factors influencing willingness to receive HPV vaccination were analyzed.Results For a total of 1314 participants with valid responses,the HPV awareness and HPV vaccine knowledge rates were 61.49%and 66.13%,respectively,and the HPV vaccine uptake rate was 74.73%.Multivariate logistic regression analysis showed that participants who were female(odds ratio[OR]=2.15,95%confidence interval[95%CI]:1.60–2.80),lived in an urban area(OR=1.56,95%CI:1.20–2.02),and from the Pearl River Delta region(OR=3.64,95%CI:2.28–5.81)and the northern region of the province(OR=5.65,95%CI:4.00–7.97)were more likely to have heard of HPV,and the participants were female(OR=2.11,95%CI:1.60–2.78),lived in an urban area(OR=1.45,95%CI:1.11–1.89),and from the Pearl River Delta region(OR=5.20,95%CI:3.06–8.83)and the northern region of the province(OR=6.30,95%CI:4.39–9.06)were more likely to have heard of HPV vaccine;the results also showed that the participants who were female(OR=7.07,95%CI:4.89–10.21),had heard of HPV(OR=1.94,95%CI:1.29–2.93),and were aware of HPV vaccine(OR=1.65,95%CI:1.07–2.55)were more likely to be willing to receive HPV vaccination.Conclusion Awareness of HPV and knowledge of HPV vaccine are not high among senior primary school students in Guangdong province,but willingness to receive HPV vaccination is relatively high.Residential area,living region and gender are the main factors influencing HPV awareness and HPV vaccine knowledge and willingness to receive HPV vaccination among the students.