新型冠状病毒感染者死亡影响因素研究进展

A review of research progress on factors influencing death in COVID-19 patients

新型冠状病毒(简称“新冠病毒”)感染是指新冠病毒感染引起的急性呼吸道传染病,多数感染者表现为无症状或者轻症,如咽干、咽痛、咳嗽、发热等,但少数感染者可进展为重症,甚至死亡。本研究检索了2020年1月1日—2022年12月31日国内外发表的有关新冠病毒感染死亡的相关报道或文献,从临床、个体、社会人文、政府干预措施和病毒株5个方面概述了新冠病毒感染者死亡的影响因素,以期为预防新冠病毒感染者的不良结局提供科学依据,并为完善感染者的治疗方案提供理论支持。

Coronavirus disease 2019(COVID-19),caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),is an acute respiratory infection.The majority of infected individuals present with either asymptomatic or mild symptoms,such as dry throat,sore throat,cough,and fever.However,a small percentage of patients may progress to severe illness and even mortality.This study conducted a comprehensive review of relevant reports and literature on COVID-19-related deaths published nationally and internationally between January 1,2020 and December 31,2022.The factors influencing death in COVID-19 patients are summarized from five perspectives:clinical manifestations,individual characteristics,socio-cultural influences,governmental interventions,and viral strains.The objective is to provide scientific evidence for the prevention of adverse outcomes in COVID-19 patients and theoretical support for the enhancement of treatment protocols.