2024版《梅毒实验室检测建议》的解读

Interpretation of 2024 edition of syphilis laboratory testing recommendations

自21世纪初以来,梅毒(syphilis)在全球发病率大幅回升,然而梅毒尚无有效疫苗进行预防。因此防控的手段主要依靠早期诊断发现传染源并进行治疗,所以在公共卫生方面,实验室诊断对防控梅毒流行发挥着关键作用。2024年2月8日美国疾病预防与控制中心(Centers for Disease Control and Prevention,CDC)发布了《梅毒实验室检测建议》,不仅详细描述了目前梅毒血清学诊断的现状,还对病原学检测方法及快速检测性能特点加以阐述。为方便中国从事梅毒诊疗的医护人员和技术人员等学习、研究和借鉴,现就2024版《梅毒实验室检测建议》核心要点进行解读。

Since the beginning of the 21st century,the global incidence rate of syphilis has risen sharply.However,there is no effective vaccine to prevent this disease.Prevention and control of syphilis mainly rely on early diagnosis and timely therapy against pathogens,so the laboratory testing and diagnostic strategies play a key role in public health response to the syphilis epidemic.On February 8,2024,the U.S.Centers for Disease Control and Prevention released the recommendations for syphilis laboratory testing(titled“CDC Laboratory Recommendations for Syphilis Testing,United States,2024”),which not only detailed the current status of syphilis serological diagnosis,but also elaborated on the characteristics of pathogenic detection methods and rapid detection performances.It is worth studying and learning by medical and technical personnel engaged in syphilis diagnosis and treatment in China.Now,the core points are interpreted in this paper.