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阴茎头局部注射透明质酸治疗早泄的方法详解和经验分享

Detailed explanation and experience sharing of local injection of hyaluronic acid into glans penis for the treatment of premature ejaculation
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摘要 早泄(PE)是男性常见的射精功能障碍,发病率较高,是导致患者及其伴侣性满意度低的常见原因。其病因复杂,受到心理、解剖、神经生物和行为医学等因素影响,难以彻底治愈。目前针对PE的治疗,除了心理干预、局部麻醉剂、达泊西汀等药物和手术治疗外,透明质酸(HA)凝胶注射也是一种可替代的治疗方法。该方法通过阴茎头局部皮下注射HA凝胶来阻断神经末梢的感觉传入,降低阴茎头的敏感性,延长患者阴道内射精潜伏时间,提高患者及其伴侣性满意度。HA凝胶具有安全性及耐受性高等优点,是一种有前景的临床应用材料。本文在探讨PE的其他疗法的同时,详细介绍了HA凝胶注射治疗的注射技术、有效性和安全性。 Premature ejaculation(PE),a common ejaculatory dysfunction in men with high prevalence,is a frequent cause of low sexual satisfaction for both patients and their partners.The etiology of PE is complex,including psychological,anatomical,neurobiological,and behavioral medicine factors,making it difficult to cure.Currently,treatments of PE include psychological interventions,local anesthetics,medications such as dapoxetine,and surgical treatments.Hyaluronic acid(HA)gel injection is an alternative treatment method.By subcutaneously injecting HA gel into the glans penis,the sensory input from nerve endings can be blocked,thereby reducing glans sensitivity.This approach can significantly extend the intravaginal ejaculatory latency time(IELT)and improve patient satisfaction.Moreover,it has advantages such as safety and high tolerability,making it a promising treatment option.In this paper,the technique,efficacy and safety of HA injection therapy for PE are introduced in detail on the basis of exploring other therapies for PE.
作者 张晓威 何海龙 胡显辉 ZHANG Xiaowei;HE Hailong;HU Xianhui(Department of Urology,Peking University People's Hospital,Beijing 100044;Institute of Applied Lithotripsy Technology,Peking University,Beijing 100044;Department of Urology,The Third Affiliated Hospital of Chongqing Medical University,Chongqing 401120;Department of Urology,Chengdu First People's Hospital,Chengdu 610016,China)
出处 《现代泌尿外科杂志》 CAS 2024年第11期945-950,共6页 Journal of Modern Urology
关键词 早泄 透明质酸 局部注射 阴道内射精潜伏时间 premature ejaculation hyaluronic acid local injection intravaginal ejaculatory latency time
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  • 1吴宇博,宋凤英.星状神经节阻滞联合西地那非治疗阳痿的疗效对照分析[J].四川精神卫生,2007,20(1):7-8. 被引量:1
  • 2Waldinger MD.Premature ejaculation:definition and drug treatment[J].Drugs,2007,67(4):547-68.
  • 3Waldinger MD,Hengeveld MW,Zwinderman AH,Olivier B.Effect of SSRI antidepressants on ejaculation:a double-blind,randomized,placebo-controlled study with fluoxetine,fluvoxamine,paroxetine,and sertraline[J].Clin Psychopharmacol,1998,8(4):274-81.
  • 4Basar MM,Yilmaz E,Ferhat M,Basar H,Batislam E.Terazosin in the treatment of premature ejaculation:a short-term follow-up[J].Int Urol Nephrol,2005,37(4):773-7.
  • 5Cavallini G.Alpha-1 blockade pharmacotherapy in primitive psychogenic premature ejaculation resistant to psychotherapy[J].Eur Urol,1995,28(2):126-30.
  • 6American Psychiatric Association,Diagnostic Criteria from DSM-IV.Washington,Dc,1994:236-237.
  • 7McMahon CG,Althof SE,Waldinger MD,et al.An evidence-based definition of lifelong premature ejaculation:report of the International Society for Sexual Medicine (ISSM) ad hoc committee for the definition of premature ejaculation[J].Sex Med,2008,5(7):1590-606.
  • 8McMahon CG,Abdo C,Incrocci L,Perelman M,Rowland D,Waldinger M,Xin ZC.Disorders of orgasm and ejaculation in men[J].Sex Med,2004,1(1):58-65.
  • 9Khatun S,Kanayama N,et al.The impact of vasoactive peptides on nitric oxide production in cultured sympathetic neurons[J].Neuroscience,1999,93:605-609.
  • 10Steinle JJ,Krizsna-Agbss D,et al.Regional regulation of chroidal blood flow by autonomic innervaton in the rat[J].Am J Physiol Regul Integr Comp Physiol,2000,279(1):202-209.

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