保妇康栓联合左氧氟沙星氯化钠注射液治疗对急性盆腔炎患者的应用效果

Effect of Baofukang Suppository Combined with Levofloxacin Sodium Chloride Injection on Patients with Acute Pelvic Inflammatory Disease

目的探讨保妇康栓联合左氧氟沙星氯化钠注射液治疗急性盆腔炎患者的应用效果。方法选取2022年12月—2023年12月曹县人民医院收治的60例急性盆腔炎患者为研究对象,按随机数字表法将其分为对照组和观察组,各30例。对照组采用左氧氟沙星氯化钠注射液治疗,观察组在对照组基础上联合保妇康栓治疗。比较两组的临床疗效、症状消失时间、炎症因子水平、盆腔指标及不良反应发生情况。结果观察组治疗总有效率为93.33%,高于对照组的73.33%,差异有统计学意义(P<0.05);观察组下腹疼痛、白带异常、腹部坠胀及炎性包块症状消失时间均短于对照组,组间差异有统计学意义(P<0.05);观察组C反应蛋白、肿瘤坏死因子-α及白细胞介素-6水平均低于对照组,组间差异有统计学意义(P<0.05);观察组盆腔炎性包块直径短于对照组,盆腔积液深度浅于对照组,组间差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论保妇康栓联合左氧氟沙星氯化钠治疗急性盆腔炎效果确切,可加快临床症状消除,减轻炎症反应,安全性较好。

Objective To explore the therapeutic effect of Baofukang Suppository combined with levofloxacin sodium chloride injection on patients with acute pelvic inflammatory disease.Methods Sixty patients with acute pelvic inflammatory disease admitted to Caoxian People's Hospital from December 2022 to December 2023 were selected as the research objects,and were divided into a control group and an observation group according to random number table method,with 30 cases in each group.The control group was treated with levofloxacin sodium chloride injection,and the observation group received combined treatment with Baofukang suppository on the basis of the control group.The clinical efficacy,the time of symptom disappearance,the level of inflammatory factors,pelvic indicators and the occurrence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 93.33%,which was higher than 73.33%of the control group,and the difference was statistically significant(P<0.05);the symptoms of lower abdominal pain,abnormal leucorrhea,abdominal distension and inflammatory mass disappeared in observation group were shorter than those in control group,and the differences between the groups were statistically significant(P<0.05);the levels of C-reactive protein,tumor necrosis factor-αand interleukin-6 in observation group were lower than those in control group,and the differences between the groups were statistically significant(P<0.05);the diameter of pelvic inflammatory mass in the observation group was shorter than that in the control group,and the depth of pelvic effusion was shallower than that in the control group,and the differences between the groups were statistically significant(P<0.05);there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Baofukang suppository combined with levofloxacin sodium chloride in the treatment of acute pelvic inflammatory disease is effective,can accelerate the elimination of clinical symptoms,reduce inflammatory response,and has good safety.