中西医综合治疗急性缺血性脑卒中的临床疗效观察

Observation on the clinical efficacy of integrated traditional Chinese and Western medicine in the treatment of acute ischemic stroke

目的 使用中西医结合方案治疗急性缺血性脑卒中,观察对患者日常活动能力等指标的影响及临床疗效。方法 选择2022年2月至2023年8月山东第二医科大学附属高密市人民医院神经内科治疗的80例急性缺血性脑卒中患者,按照随机数表法分组,治疗组、对照组各40例。全部患者给予双重抗血小板聚集、神经康复训练等基础治疗,治疗组在此基础上给予“加味补气还阳方”,采用中西医结合治疗。以外周血内皮祖细胞、血管内皮生长因子、基质细胞衍生因子-1等血液因子,美国国立卫生研究院卒中量表评分、改良Barthel指数为监测指标,评价治疗效果。结果 两组治疗后血液因子指标较治疗前升高,差异有统计学意义(P <0.05);治疗组血液因子高于对照组,差异有统计学意义(P <0.05);两组治疗后量表评分显著改善(P <0.05),治疗组优于对照组,差异有统计学意义(P <0.05)。结论 使用中西医结合治疗方案,患者神经功能缺损改善更显著,对急性缺血性脑卒中预后意义重大。

Objective To use integrated traditional Chinese and Western medicine to treat acute ischemic stroke,and to observe the impact on daily activity and other indicators of patients,as well as clinical efficacy.Methods A total of 80 patients with acute ischemic stroke who were treated in the Department of Neurological Rehabilitation,Gaomi People’s Hospital Affiliated to Shandong Second Medical University from February 2022 to August 2023 were divided into treatment group and control group by random number table method,with 40 patients in each group.All patients were given basic treatment such as dual antiplatelet aggregation and neurological rehabilitation training,and the treatment group was given"Jiawei Buqi Huanyang Decoction"on this basis,and was treated with integrated traditional Chinese and Western medicine.Peripheral blood endothelial progenitor cells,vascular endothelial growth factor,stromal cell-derived factor-1 and other blood factors,as well as the National Institutes of Health Stroke Scale and modified Barthel index were used as monitoring indicators to evaluate the therapeutic effect.Results The blood factor indicators of the two groups increased significantly after treatment compared to before treatment(P<0.05).The blood factors in the treatment group were higher than those in the control group,and the difference was statistically significant(P<0.05).The scale scores of the two groups improved significantly after treatment(P<0.05),and the treatment group performed better than the control group,with a statistically significant difference(P<0.05).Conclusion The use of integrated traditional Chinese and Western medicine treatment plan can significantly improve the neurological function of patients,which is of great significance for the prognosis of acute ischemic stroke.