摘要
目的 研究对重症脓毒血症患者实施血液灌流、连续性血液净化联合方案进行治疗的临床效果。方法非随机选取2021年12月—2023年12月在牡丹江医科大学附属红旗医院重症医学科接受治疗的80例重症脓毒血症患者作为研究对象,按治疗方法不同分为观察组与对照组,每组40例患者。对照组接受连续性血液净化治疗,观察组开展血液灌流结合连续性血液净化方案,分析对比两组治疗效果。结果 治疗后,观察组患者体内的炎性因子水平低于对照组,同时呼吸频率和心率优于对照组,差异有统计学意义(P均<0.05);观察组病情改善评分为(10.13±2.01)分,低于对照组的(15.27±2.56)分,差异有统计学意义(t=9.987,P<0.05)。结论 运用血液灌流、连续性血液净化两种方式联合治疗重症脓毒血症,可及时改善患者的体内炎性因子水平,确保患者生命体征平稳,提高疾病控制效果。
Objective To study the clinical effect of combining hemoperfusion and continuous blood purification regi-men in patients with severe sepsis.Methods Eighty patients with severe sepsis treated in the Intensive Care Depart-ment of Hongqi Hospital Affiliated to Mudanjiang Medical University from December 2021 to December 2023 were non-randomly selected as the research objects.They were divided into observation group and control group by differ-ent treatment methods,with forty patients in each group.The control group received continuous blood purification for treatment,and the observation group carried out the hemoperfusion combined with continuous blood purification scheme.Analyzed and compared the treatment effects of the two groups.Results After treatment,the levels of inflam-matory factors in the observation group patients were lower than those in the control group,and the respiratory rate and heart rate were better than those in the control group,the differences were statistically significant(all P<0.05).The final observation group's condition improvement score was 10.13±2.01,lower than the control group 15.27±2.56,the difference was statistically significant(t=9.987,P<0.05).Conclusion The combination of blood perfusion and con-tinuous blood purification in the treatment of severe sepsis can timely improve the levels of inflammatory factors in the patient's body,ensure stable vital signs,and enhance disease control effectiveness.
作者
张力丹
张雪娇
安平
张国琨
王健博
李加姝
ZHANG Lidan;ZHANG Xuejiao;AN Ping;ZHANG Guokun;WANG Jianbo;LI Jiashu(Department of Critical Care Medicine,Hongqi Hospital Affiliated to Mudanjiang Medical University,Mudanjiang 157011,Heilongjiang,China)
出处
《系统医学》
2024年第19期57-59,67,共4页
Systems Medicine