血清降钙素原联合尿常规检查在成人尿路感染患者临床诊断中的应用价值探析

Application Value of Serum Procalcitonin Combined with Routine Urine Examination in the Clinical Diagnosis of Adult Patients with Urinary Tract Infection

目的:探析血清降钙素原(PCT)联合尿常规检查在成人尿路感染(UTI)患者临床诊断中的应用价值。方法:回顾性分析2020年1月—2022年12月济宁市第三人民医院收治的80例疑似UTI患者资料。所有患者均进行PCT、尿常规及尿细菌培养检查。分析尿细菌培养结果,以尿细菌培养结果作为金标准,比较白细胞数量、红细胞数量、亚硝酸盐、PCT单项与四项联合的诊断结果。结果:80例疑似UTI患者经尿细菌培养证实UTI患者有62例,无UTI患者有18例;四项联合诊断灵敏度为96.77%,准确度为95.00%,均高于白细胞数量单项检测的88.00%、70.00%、红细胞数量单项检测的87.75%、68.75%、亚硝酸盐单项检测的88.23%、71.25%及血清PCT单项检测的92.00%、73.75%,差异均有统计学意义(P<0.05);白细胞数量、红细胞数量、亚硝酸盐、血清PCT单项检测与四项联合诊断的特异度比较,差异均无统计学意义(P>0.05)。结论:血清PCT联合尿常规检查用于成人UTI诊断,可提高疾病的诊断灵敏度及准确度。

Objective:To explore the clinical value of serum procalcitonin(PCT)combined with routine urine examination in the diagnosis of adult urinary tract infection(UTI).Methods:Data of 80 patients with suspected UTI admitted to The Third People’s Hospital of Jining from January 2020 to December 2022 were retrospectively analyzed.PCT,urine routine and urine bacterial culture were performed in all patients.The results of urine bacterial culture were analyzed,and the results of urine bacterial culture were used as the gold standard to compare the diagnostic results of the number of white blood cells,the number of red blood cells,nitrite and PCT.Results:Of the 80 suspected patients with UTI,62 patients with UTI and 18 patients without UTI were confirmed by urinary bacterial culture.The sensitivity and accuracy of the combined diagnosis were 96.77%and 95.00%respectively.They were higher than 88.00%and 70.00%of single detection of white blood cell count,87.75%and 68.75%of single detection of red blood cell count,88.23%and 71.25%of single detection of nitrite,92.00%and 73.75%of single detection of serum PCT,with statistical significance(P<0.05).There was no significant difference in the specificity of the single detection of white blood cell count,red blood cell count,nitrite and serum PCT compared with the four combined diagnoses(P>0.05).Conclusion:Serum PCT combined with urine routine examination can improve the sensitivity and accuracy of the diagnosis of adult UTI.