多种油脂肪乳注射液在新生儿营养支持中的临床应用研究进展

Advances in clinical application of muti-oil fat emulsion in neonatal nutritional support

脂肪乳注射液是肠外营养支持治疗中的重要组成部分,可为人体提供更均衡的能量和必需脂肪酸。多种油脂肪乳是适用于儿科的含鱼油的脂肪乳注射液,其含有更多的维生素E和更少的植物甾醇,二十碳五烯酸、二十二碳六烯酸含量更高,抗炎性更强。此外,其脂肪酸谱与母乳接近,能够为新生儿提供更均衡高效的营养支持。目前多种油脂肪乳已广泛应用于临床,但国内关于多种油脂肪乳注射液在新生儿临床应用方面的研究报道较少,因此本文对多种油脂肪乳注射液在新生儿营养支持方面的临床研究进展进行了综述。

Fat emulsion injection is an important component of parenteral nutritional support therapy,providing the body with a more balanced supply of energy and essential fatty acids.Multi-oil lipid emulsions are fish oil-containing lipid emulsions suitable for pediatric use.They contain higher levels of vitamin E and lower levels of phytosterols,as well as increased amounts of eicosapentaenoic acid(EPA)and docosahexaenoic acid(DHA),contributing to stronger anti-inflammatory properties.Furthermore,their fatty acid profile closely resembles that of human breast milk,enabling them to provide more balanced and effective nutritional support for neonates.While multi-oil lipid emulsions have been widely used clinically,there are limited research reports on their application in neonates in China.This article reviews the progress of clinical research on the application of multi-oil lipid emulsions in neonatal nutritional support.