儿童医疗辅导游戏对提高难治性癫痫患儿生酮饮食治疗依从性和酮症状态的效果研究

Effect of children's medical counseling games on improving compliance with ketogenic diet and ketosis status in children with drug-refractory epilepsy

目的探讨儿童医疗辅导游戏在药物难治性癫痫患儿生酮饮食治疗中的应用效果。方法采用随机数字表法,选取2023年1月-2024年6月在深圳市儿童医院神经内科病房住院的药物难治性癫痫且第一次使用生酮饮食治疗的患儿共98例为研究对象,分为观察组(n=49)和对照组(n=49)。对照组接受传统的多学科团队健康教育模式,而观察组在接受多学科团队健康教育模式生酮饮食治疗的基础上同时参与定制的医疗辅导游戏干预,比较两组患儿达到酮症状态的时间、生酮饮食照顾者知识水平、生酮饮食患儿保留率。结果观察组达到酮症状态的时间早于对照组(P<0.05)。观察组生酮饮食主要照顾者知识水平,生酮饮食患儿第3、6个月保留率均高于对照组(P<0.05)。结论医疗辅导游戏在药物难治性癫痫生酮饮食中的应用是一种有效的治疗策略,有利于药物难治性癫痫患儿尽早达到酮症状态,可以提高生酮饮食照顾者知识水平,提高生酮饮食患儿保留率,发挥优化临床治疗效果的作用,可促进药物难治性癫痫患儿生活质量的提高。

Objective To investigate the effect of medical counseling games on ketogenic diet therapy for drug-resistant epilepsy children.Methods A total of 98 children with drug-resistant epilepsy admitted to the neurology ward of Shenzhen Children's Hospital from January 2023 to June 2024 who were treated with ketogenic diet for the first time were selected as the study objects by random number table method,and were divided into observation group(n=49)and control group(n=49).The control group received the traditional multidisciplinary team health education mode,while the observation group received the ketogenic diet treatment based on the multidisciplinary team health education mode and participated in the customized medical counseling games intervention.The time of children reaching ketosis,the knowledge level of ketogenic diet caregivers and the retention rate of children on ketogenic diet were compared between the two groups.Results The time of ketosis in observation group was earlier than that in control group(P<0.05).The knowledge level of the main caregivers of ketogenic diet and the retention rate of children with ketogenic diet at 3 months and 6 months in observation group were higher than those in control group(P<0.05).Conclusion The use of medical counseling games in the ketogenic diet for medically refractory epilepsy is an effective therapeutic strategy that facilitates the early attainment of ketosis in children with medically refractory epilepsy,improves the knowledge of caregivers on the ketogenic diet,improves retention of children on the ketogenic diet,and serves to optimize the effectiveness of clinical outcomes,which may contribute to the quality of life of children with medically refractory epilepsy.