2型糖尿病药物依从性概览及治疗方案优化

Overview of medication adherence and treatment optimization for type 2 diabetes mellitus

T2DM是我国严重的公共健康问题.BG控制不佳可升高微血管、大血管并发症及死亡风险.T2DM治疗中患者对临床治疗方案的依从性,是影响DM控制的关键因素.基于此,本文梳理了不同降糖方案相关依从性研究,分析阐述药物特性、患者因素及医患共同决策对患者依从性的影响,探讨T2DM治疗管理的优化策略,以提高患者药物依从性,改善临床结局.

Type 2 diabetes mellitus(T2DM)is a serious public health issue in China.Poor glycemic control is closely related to increased risks of microvascular,macrovascular events and mortality.Self‑management ability and treatment adherence are key factors affecting glycemic control.Based on this,this review summarizes the findings on medication adherence related to different glucose‑lowering regimens,analyzes the factors affecting patient treatment adherence and discusses the roles of drug characteristics,patient factors and shared decision‑making in optimizing T2DM management strategies,in the hope of improving clinical outcomes.