罕见部位后纵隔髓性脂肪瘤1例报告及文献综述

The Myeloliposoma in the Seldom Position of the Posterior Mediastina:a Case Report and Review of the Literature

髓性脂肪瘤是一种罕见的良性肿瘤,大多数发生在肾上腺,发生肾上腺外的病例较少。本文报道1例体检时发现在后纵隔占位性病变,经影像学印诊后行手术切除,并得到病理学明确诊断。镜下肿瘤由成熟脂肪和骨髓组织组成。骨髓可见正常髓系、红系和巨核细胞三系造血细胞,巨核细胞较多。结合病例分析和新近文献进展,总结髓性脂肪瘤的临床病理特征和发病机制,对本病的诊断与鉴别诊断以及临床处置进行讨论,以提高对本病的认识并防止误诊。

Myellary lipoma is a rare benign tumor,most of which occurs in the adrenal gland,with fewer cases occurring outside the adrenal gland.This paper reported a case of posterior mediastinum during physical examination,which was surgical removed after imaging printing,and a clear pathological diagnosis was obtained.The tumors consisted of mature fat and bone marrow tissue by microscopically.In the bone marrow,normal hematopoietic cells of myeloid,erythroid and megakaryocyte were visible,with more megakaryocytes.Combining case analysis and recent progress in the literature,the clinicopathological characteristics and pathogenesis of myeloid lipoma were summarized,and the diagnosis,differential diagnosis and clinical management of this disease were discussed,so as to improve the understanding of the disease and prevent misdiagnosis.