阿奇霉素序贯疗法治疗小儿肺炎支原体肺炎的临床价值研究

Study on the Clinical Value of Azithromycin Sequential Therapy in the Treatment of Pediatric Mycoplasma Pneumoniae Pneumonia

目的:探讨阿奇霉素序贯疗法治疗小儿肺炎支原体肺炎的效果。方法:选取2022年6月—2024年6月合肥市妇幼保健院收治的62例小儿肺炎支原体肺炎患儿为研究对象,随机分为对照组和观察组,每组31例。对照组采用罗红霉素序贯疗法,观察组采用阿奇霉素序贯疗法。对比两组症状消失时间、临床疗效、不良反应发生率。结果:观察组咳嗽、喘憋、气促及哮鸣音消失时间均短于对照组(P<0.05);观察组治疗总有效率高于对照组(P=0.017);观察组不良反应发生率低于对照组(P=0.013)。结论:阿奇霉素序贯疗法治疗小儿肺炎支原体肺炎的效果显著,可有效促进临床症状消退,降低不良反应发生率。

Objective:To investigate the effect of azithromycin sequential therapy in the treatment of pediatric mycoplasma pneumoniae pneumonia.Methods:Sixty-two cases of pediatric mycoplasma pneumoniae pneumonia admitted to Hefei Maternal and Child Health Hospital from June 2022 to June 2024 were selected as the study subjects and randomly divided into the control group and the observation group,with thirty-one cases in each group.The control group was treated with roxithromycin sequential therapy,and the observation group was treated with azithromycin sequential therapy.Compare the time of symptom disappearance,clinical efficacy and incidence of adverse reactions in the two groups.Results:The disappearance time of cough,wheezing,shortness of breath and rales in the observation group was shorter than that in the control group(P<0.05);the total effective rate of treatment in the observation group was higher than that in the control group(P=0.017);the incidence rate of adverse reactions in the observation group was lower than that in the control group(P=0.013).Conclusion:Azithromycin sequential therapy is effective in treating pediatric mycoplasma pneumoniae pneumonia,which can effectively promote the subsidence of clinical symptoms and reduce the incidence of adverse reactions.