经皮椎体后凸成形术治疗骨质疏松性脊柱骨折的临床有效性研究

Clinical Effectiveness of Percutaneous Kyphoplasty in the Treatment of Osteoporotic Spinal Fractures

目的:观察经皮椎体后凸成形术治疗骨质疏松性脊柱骨折的临床有效性。方法:将临沂市精神卫生中心2022年4月—2024年4月收治的80例骨质疏松性脊柱骨折患者基于数字表随机法均分为对照组(经皮椎体成形术)与观察组(经皮椎体后凸成形术),各40例。比较两组患者炎性因子水平、疼痛程度、脊柱影像指标、术后并发症发生率。结果:术后48 h,两组C反应蛋白、白细胞计数、白细胞介素-6水平均低于术前,观察组低于对照组(P<0.05);术后48 h,两组视觉模拟评分法评分均低于术前,观察组低于对照组(P<0.001);术后1周,两组Cobb角、椎体矢状面指数、椎体前缘高度均高于术前,观察组高于对照组(P<0.05);观察组术后并发症发生率低于对照组(P=0.018)。结论:骨质疏松性脊柱骨折患者应用经皮椎体后凸成形术的治疗效果优于经皮椎体成形术,可有效降低机体炎性因子水平,缓解术后躯体痛感,促进脊柱影像指标改善,降低术后并发症发生率。

Objective:To observe the clinical effectiveness of percutaneous kyphoplasty in the treatment of osteoporotic spinal fractures.Methods:A total of eighty patients with osteoporotic spinal fracture admitted to Linyi Mental Health Center from April 2022 to April 2024 were divided into control group(percutaneous vertebroplasty)and observation group(percutaneous kyphoplasty)based on numerical table randomization method,with forty cases each.The levels of inflammatory factors,pain degree,spinal imaging indexes and postoperative complications were compared between the two groups.Results:48 h after operation,the levels of C-reactive protein,white blood cell count and interleukin-6 in two groups were lower than before operation,and the observation group was lower than control group(P<0.05);48 h after surgery,the scores of visual analog score in both groups were lower than before surgery,and the observation group was lower than the control group(P<0.001);one week after surgery,the Cobb Angle,sagittal plane index of vertebral body and anterior margin height of vertebral body in two groups were higher than before surgery,and the observation group was higher than control group(P<0.05);the incidence of postoperative complications in observation group was lower than that in control group(P=0.018).Conclusion:The therapeutic effect of percutaneous kyphoplasty in patients with osteoporotic spinal fractures is better than that of percutaneous vertebroplasty,which can effectively reduce the level of inflammatory factors,relieve postoperative physical pain,promote the improvement of spinal imaging indicators,and reduce the incidence of postoperative complications.