他汀类药物的不良反应及相关因素分析

Analysis of Adverse Reactions and Related Factors of Statins

文章探讨了他汀类药物的常见不良反应,重点分析了阿托伐他汀钙片、辛伐他汀片、瑞舒伐他汀钙片、匹伐他汀钙片、普伐他汀钠片等的相关问题。他汀类药物在降低胆固醇水平的同时,可能引发肌肉疼痛、肝功能异常和胃肠不适等不良反应。相关因素分析表明,不良反应的发生与药物剂量、个体差异及药物相互作用密切相关。通过了解这些不良反应及其影响因素对提高临床用药安全性具有重要意义。

This article discussed the common adverse reactions of statins,and mainly analyzed the related problems of atorvastatin calcium tablets,simvastatin tablets,Rosuvastatin calcium tablets,Pivastatin calcium tablets and pravastatin sodium tablets.While lowering cholesterol levels,statins can cause side effects such as muscle pain,abnormal liver function and gastrointestinal upset.Analysis of related factors showed that the occurrence of adverse reactions was closely related to drug dose,individual differences and drug interactions.Understanding these adverse reactions and their influencing factors is of great significance to improve clinical drug safety.