更年期代谢综合征女性患者用药依从性的影响因素分析

Analysis of medication compliance and influencing factors in female patients with menopausal metabolic syndrome

目的 探究更年期代谢综合征女性患者用药依从性的影响因素。方法 选取2021年1月1日至2023年6月30日就诊的更年期代谢综合征女性患者200例作为研究对象,收集患者年龄、教育程度、家庭人均月收入、婚姻状况、家庭支持程度、疾病认知程度、药物不良反应和居住地等一般资料。采用Morisky用药依从性量表评估患者用药依从性。发放调查问卷200份,回收有效问卷194份,有效回收率为97.00%。采用单因素及多因素Logistic回归分析影响更年期代谢综合征女性患者用药依从性的因素。结果 194例患者中,71例(占36.60%)用药依从性中等,123例(占63.40%)用药依从性良好。单因素分析发现,教育程度、家庭人均月收入、家庭支持程度、疾病认知程度、药物不良反应和居住地是影响更年期代谢综合征女性患者用药依从性的因素(P<0.05)。进一步行多因素Logistic回归分析发现,教育程度(OR=1.915,95% CI:1.141~3.213)、家庭人均月收入(OR=2.273,95% CI:1.200~4.306)、家庭支持程度(OR=1.761,95% CI:1.094~2.835)、疾病认知程度(OR=2.641,95% CI:1.194~5.841)、药物不良反应(OR=1.548,95% CI:1.036~2.314)和居住地(OR=2.236,95% CI:1.117~4.475)是更年期代谢综合征女性患者用药依从性的独立危险因素(P<0.05)。结论 教育程度、家庭人均月收入、家庭支持程度、疾病认知程度、药物不良反应和居住地是更年期代谢综合征女性患者用药依从性的影响因素,应针对此类患者及时开展用药指导和健康宣教,提高用药依从性,进而提高疗效。

AIM To explore the influencing factors of medication compliance in female patients with menopausal metabolic syndrome. METHODS A total of 200 patients with menopausal metabolic syndrome were collected as observation subjects from January 2021 to June 2023. General data of patients such as age, education level, family monthly per capita income, marital status, family support, disease awareness, adverse drug reactions and residence were collected. Morisky Medication Adherence Scale was applied to determine the medication compliance of all patients.A total of 200 questionnaires were distributed and 194 valid questionnaires were recovered, with an effective recovery rate of 97.00%. Univariate and multivariate Logistic regression were applied to analyze the factors affecting medication adherence in female patients with menopausal metabolic syndrome. RESULTS Among 194 patients, 71 patients(36.60%)exhibited moderate medication adherence, while 123 patients(63.40%) demonstrated good medication adherence.Univariate analysis revealed that education level, monthly per capita family income, the degree of family support, disease awareness, adverse drug reactions, and residence were factors that influenced medication adherence in women with menopausal metabolic syndrome(P<0.05). Further multivariate Logistic regression analysis revealed that education level(OR=1.915, 95% CI:1.141-3.213), monthly per capita family income(OR=2.273, 95% CI:1.200-4.306), family support(OR=1.761, 95% CI:1.094-2.835), disease awareness(OR=2.641, 95% CI:1.194-5.841), adverse drug reactions(OR=1.548,95% CI: 1.036-2.314), residence(OR=2.236,95% CI:1.17-4.475) were risk factors for poor medication adherence in female menopausal patients with metabolic syndrome(P < 0.05). CONCLUSION Education level, per capita household income, family support, disease awareness, adverse reactions, and residence are risk factors that affect the medication compliance of female menopausal patients with metabolic syndrome. Corresponding measures should be taken promptly, and medication guidance and health education should be carried out to improve medication compliance,thereby enhancing treatment efficacy.