肺炎支原体肺炎患儿发生支气管黏液栓的危险因素分析

Risk factors for bronchial mucoid impaction in children with mycoplasma pneumoniae pneumonia

目的探讨肺炎支原体肺炎(MMP)患儿发生支气管黏液栓的危险因素。方法回顾性抽取2022年9月至2023年11月驻马店市中心医院收治的MMP患儿106例,均接受电子支气管镜检查及灌洗治疗,依据支气管黏液栓形成情况,将其分为支气管黏液栓组(42例)和无支气管黏液栓组(64例)。分析两组一般资料、临床特征、血液指标水平,通过多因素Logistic分析MMP患儿发生支气管黏液栓的高危因素。结果106例MMP患儿中发生支气管黏液栓42例(39.62%)。支气管黏液栓组热程长于无支气管黏液栓组,胸腔积液、肺不张比例高于无支气管黏液栓组,血清C反应蛋白、D-二聚体(DD)、乳酸脱氢酶、免疫球蛋白A(IgA)、水平高于无支气管黏液栓组,P均<0.05。多因素Logistic分析结果显示,热程、肺不张、DD、IgA水平升高为MMP患儿发生支气管黏液栓的高危因素(OR=2.13、1.75、1.87、1.65,P均<0.05)。结论MMP患儿发生支气管黏液栓率为39.62%,其高危因素较多,可为筛选高危患儿、制定临床防治策略提供依据。

ObjectiveTo investigate the risk factors for bronchial mucoid impaction in children with Mycoplasma pneumoniae pneumonia(MMP).MethodsA total of 106 children with MMP admitted to Zhumadian Central Hospital from September 2022 to November 2023 were selected retrospectively,all of them received electronic bronchoscopy examination and lavage treatment.And they were divided into bronchial mucoid impaction group(42 cases)and non-bronchial mucoid impaction group(64 cases)according to the occurrence of bronchial mucoid impaction.The general data,clinical characteristics and blood indexes of the two groups were analyzed.The multivariate logistic regression was used to analyze the risk factors for bronchial mucoid impaction in children with MMP.ResultsAmong the 106 children with MMP,42 cases(39.62%)had bronchial mucoid impaction.The bronchial mucoid impaction group had a longer fever duration,higher proportions of pleural effusion and pulmonary atelectasis,moreover,the bronchial mucoid impaction group had higher serum levels of C-reactive protein,D-dimer(DD),lactate dehydrogenase and immunoglobulin A(IgA)compared with the non-bronchial mucoid impaction group(all P<0.05).Results of multivariate logistic analysis revealed that the increases in fever duration,pulmonary atelectasis,and the levels of DD and IgA were the risk factors for bronchial mucoid impaction in children with MMP(OR=2.13,1.75,1.87,1.65;all P<0.05).ConclusionsThe incidence of bronchial mucoid impaction in children with MMP is 39.62%,and the disease has various high-risk factors,which can provide a basis for screening high-risk children and formulating clinical prevention and treatment strategies.