不同患肢下肢深静脉血栓患者临床特征及转归分析

Clinical Characteristics and Outcome Analysis of Patients with Lower Extremity Deep Vein Thrombosis in Different Affected Limbs

目的:探讨不同患肢下肢深静脉血栓患者临床特征及转归。方法:查阅80例下肢深静脉血栓患者的病历资料,分析患不同下肢深静脉血栓患者的临床特征及不同治疗情况的血栓转归情况。结果:双下肢血栓占比18.75%(15/80),非双下肢占比81.25%(65/80)。双下肢血栓患者年龄≥60岁、受伤至手术时间≥7 d、血红蛋白、白蛋白、红细胞比容较非下肢血栓高,活化部分凝血活酶时间短(P均<0.05)。接受治疗患者中双下肢与非双下肢深静脉血栓患者的治疗方案对比有差异,所有患者中双下肢与非双下肢深静脉血栓患者治疗转归中好转/消失占比对比有差异(P均<0.05)。治疗时间≥15 d的血栓好转/消失占比明显较未治疗组高(P<0.05)。结论:双下肢深静脉血栓的发生率为18.75%,年龄≥60岁、受伤至手术时间≥7 d、活化部分凝血活酶时间、血红蛋白、白蛋白、红细胞比容较高,临床中需重视下肢深静脉血栓的防治,若需抗凝治疗,应在综合评估风险后制定个性化治疗方案,并建议抗凝疗程≥15 d。

Objective:To investigate the clinical features and outcomes of patients with lower extremity deep vein thrombosis in different affected limbs.Methods:The medical records of 80 patients with deep venous thrombosis of lower extremity were reviewed,and the clinical characteristics and prognosis of thrombosis under different treatment conditions were analyzed.Results:The proportion of thrombus in both lower limbs was 18.75%(15/80)and 81.25%(65/80)in non-both lower limbs.Double lower extremities thrombosis patients aged 60 or higher,injury to operating time 7 d or higher,hemoglobin,albumin,red blood cell volume than in the lower extremities thrombosis is high,short part activated clotting time live enzymes(P<0.05).There were differences in the treatment plan between patients with bilateral and non-bilateral deep vein thrombosis,and there were differences in the proportion of patients with and without bilateral deep vein thrombosis in the treatment outcome(P all<0.05).Treatment time of 15 d or thrombosis better/disappear is higher than obviously less treatment group(P<0.05).Conclusion:The incidence of deep vein thrombosis of both lower extremities was18.75%.The age≥60 years old,the time from injury to operation≥7 days,activated partial thromboplasmosis time,hemoglobin,albumin,and hematocrit were higher.The prevention and treatment of deep vein thrombosis of lower extremities should be paid attention to in clinical practice.And it is recommended that the anticoagulation course≥15 d.