新生儿肺出血发病高危因素探究及行高频振荡通气治疗效果分析

Exploration of High-risk Factors for Neonatal Pulmonary Hemorrhage and Analysis of the Effectiveness of High-frequency Oscillatory Ventilation Treatment

目的:探讨新生儿肺出血发病高危因素及高频振荡通气对新生儿肺出血的治疗效果。方法:2021.1-2023.12收治的100例肺出血新生儿为观察组,100名健康新生儿为对照组,分析新生儿肺出血发病高危独立影响因素。随后将100例肺出血新生儿随机分组,常规组采取常规机械通气,高频组采取高频振荡通气。对比两组患儿相关指标。结果:早产儿、宫内窘迫、胎粪吸入、并发感染性肺炎、新生儿窒息、呼吸窘迫综合征为新生儿肺出血发病的独立因素(P<0.05);T_(2)、T_(3)、T_(4)时间两组患儿OI、PaCO_(2)均降低,且高频组低于常规组,PaO_(2)升高,高频组高于常规组(P<0.05);高频组并发症发生率明显低于常规组(P<0.05)。结论:早产儿、宫内窘迫、胎粪吸入、并发感染性肺炎、新生儿窒息、呼吸窘迫综合征为新生儿肺出血发病的独立危险因素,需采取重点监护措施,预防肺出血发生,针对肺出血新生儿可采取高频振荡通气治疗,改善患儿血气指标及预后水平,降低并发症发生率。

Objective:To explore the high-risk factors for neonatal pulmonary hemorrhage and analyze the therapeutic effect of high-frequency oscillatory ventilation on neonatal pulmonary hemorrhage.Method:100 newborns with pulmonary hemorrhage admitted from January 2021 to December 2023 were selected as the observation group,and 100 healthy newborns were selected as the control group.The independent influencing factors of the high risk of neonatal pulmonary hemorrhage were analyzed.Subsequently,100newborns with pulmonary hemorrhage were randomly divided into two groups:the conventional group received conventional mechanical ventilation,and the high-frequency group received high-frequency oscillatory ventilation.Compare the relevant indicators between two groups of pediatric patients.Results:Premature infants,intrauterine distress,meconium aspiration,concurrent infectious pneumonia,neonatal asphyxia,and respiratory distress syndrome are independent factors for the onset of neonatal pulmonary hemorrhage(P<0.05);At T_(2),T_(3),and T_(4),both groups of children showed a decrease in OI and PaCO_(2),with the high-frequency group lower than the conventional group and an increase in PaO_(2),with the high-frequency group higher than the conventional group(P<0.05);The incidence of complications in the high-frequency group was significantly lower than that in the conventional group(P<0.05).Conclusion:Premature infants,intrauterine distress,meconium aspiration,concurrent infectious pneumonia,neonatal asphyxia,and respiratory distress syndrome are independent risk factors for neonatal pulmonary hemorrhage.Key monitoring measures should be taken to prevent the occurrence of pulmonary hemorrhage.For newborns with pulmonary hemorrhage,high-frequency oscillatory ventilation treatment can be adopted to improve their blood gas indicators and prognosis,and reduce the incidence of complications.