2020—2023年浙江省温岭市结直肠癌早诊早治筛查结果分析

Results of Colorectal Cancer Screening in Wenling City of Zhejiang Province from 2020 to 2023

[目的]分析2020—2023年浙江省温岭市结直肠癌早诊早治筛查结果,为优化温岭市结直肠癌筛查策略提供参考依据。[方法]2020—2023年,采用整群抽样的方法选取浙江省温岭市50~74周岁的本市户籍居民,采用结直肠癌问卷风险评估和免疫法粪便潜血试验(fecal immunochemical test,FIT)相结合的方法初筛出结直肠癌高危人群,对其行结肠镜检查。[结果]浙江省温岭市50~74周岁结直肠癌早诊早治筛查目标人数为380177人,参与筛查人数为192205人,参与率为50.56%,高危人数(筛查阳性)为35428人,高危率为18.43%。共10213人进行结肠镜检查,依从率为28.83%;共检出病变7786例,检出率为76.24%,2023年为历年最高达80.44%;其中非腺瘤性良性病变2160例、非进展期腺瘤3403例、进展期腺瘤2048例、结直肠癌175例,检出率分别为21.15%、33.32%、20.05%和1.71%。男性非进展期腺瘤、进展期腺瘤及结直肠癌检出率均高于女性(P均<0.05)。在进展期腺瘤及结直肠癌病例中检出率前3位的城镇分别为石塘镇(32.84%)、石桥头镇(24.31%)、新河镇(23.77%)。[结论]浙江省温岭市居民患结直肠癌的风险较高,结肠镜检查依从性良好,非腺瘤性良性病变、非进展期腺瘤、进展期腺瘤的检出率均较高,且呈逐年增加态势,今后结直肠癌筛查工作较为严峻,可适当加强重点区域的防控,探索出适合本区域的筛查模式。

[Objective]To analyse the results of colorectal cancer early diagnosis and treatmen program in Wenling City of Zhejiang Province from 2020 to 2023.[Methods]From 20202023,a cluster sampling method was used to select residents aged 50~74 years in Wenling Cit All participants underwent a questionnaire survey on risk assessment of colorectal cancer an fecal immunochemical test(FIT)as initial screening,the high-risk subjects of colorectal cance were then subject to colonoscopy.[Results]Among 380177 target subjects in Wenling City,19220 people participated in screening with a participation rate of 50.56%.A total of 35428 peopl were identified as at high risk with a high risk rate of 18.43%,among whom 10213 people un derwent colonoscopy with a compliance rate of 28.83%.Colonoscopy detected 7786 lesions wit a detection rate of 76.24%,2160 were non-adenomatous benign lesions,3403 were non-pro gressing adenomas,2048 were progressing adenomas,and 175 were colorectal cancers,with detection rate of 21.15%,33.32%,20.05%and 1.71%,respectively.The detection rates o non-progressive adenomas,progressive adenomas and colorectal cancers were higher in male than those in females(all P<0.05).The top three towns with higher detection rates of progressiv adenomas and colorectal cancers were Shitang(32.84%),Shiqiaotou(24.31%)and Xinh(23.77%).[Conclusion]Residents of Wenling City have a high risk of colorectal cancer;th compliance of colonoscopy is generally good;the detection rates of non-adenomatous benig lesions,non-progressing adenomas,and progressing adenomas are high and show a increasin trend from 2020 to 2023.