鹰爪花属植物化学成分和生物活性的研究进展

Research progress on chemical constituents and biological activities of Artabotrys plants

鹰爪属植物在全球范围内现存100多种,在我国有4种,主要分布在南部,有悠久的药用历史,主要用于疟疾、风湿等顽疾。经现代药化学和药理学研究证实该属植物的化学成分种类多样,涉及十几个分类,主要有生物碱类、萜类、甾体类、环己烯类、黄酮类、醌类、苯丙素类及挥发油等,生物活性也十分丰富,具有抗肿瘤、抗菌、抗病毒、抗疟、抗虫、抗生育、抗凝血、抗血小板、抗氧化和细胞保护作用等。本文对其化学成分和生物活性进行详细综述,为其资源开发研究奠定了理论基础。

There are more than 100 kinds of Artabotrys plants extant in the world.There are four species in China,which are mainly distributed in the south and people have a long medicinal history,mainly using it for malaria,rheumatism and other stubborn diseases.Modern pharmacochemical and pharmacological studies have confirmed that the chemical constituents of Artabotrys plants are diversified,involving more than a dozen categories,including alkaloids,terpenoids,cyclohexenes,steroids,flavonoids,quinones,phenylpropanes and volatile oils,etc.The biological activities of this genus are also very rich,with anti-tumor,antibacterial,antiviral,antimalarial,anti-insect,antifertility,antithrombin,antiplatelet,antioxidative,cytoprotection and so on.In this paper,the chemical constituents and biological activities of the plant were reviewed in detail,which laid a theoretical foundation for its resource development.