Research Progress on the Synthesis of Benzofuran Based on Cyclization Strategy

基于成环策略构建苯并呋喃的合成研究

Benzofuran is an essential structural component found in a wide range of natural products,agrochemicals and drugs,possessing a range of biological activities.In recent years,there have been numerous reports of successful syntheses of benzofuran derivatives via intra-and inter-molecular cyclizations using diverse catalysts.This review gives an exhaustive and methodical survey of the procedures for making benzofurans.

苯并呋喃是一种重要的结构成分,存在于各种天然产品、农用化学品和药物中,一直以来受到广大化学家的广泛关注.近年来,通过分子内和分子间环化合成苯并呋喃衍生物的报道不胜枚举,主要有金属催化反应合成、电催化反应合成、光催化反应合成以及其他的合成方法,并且对其反应机理进行了详细的研究,重点针对环化合成苯并呋喃衍生物进行了详细且系统的总结.