中医分期辨证论治联合覆盖式VSD技术治疗舟山眼镜蛇咬伤的临床观察

Clinical Study on the Application of Traditional Chinese Medicine Syndrome Differentiation and Staged Treatment Combined with Coverage-style VSD Technology in Patients with Naja Atra Bite

目的观察中医分期辨证论治联合覆盖式VSD技术对舟山眼镜蛇咬伤早期肿胀与疮疡及血清CK表达的临床效果。方法患者120例随机分为治疗组与对照组各60例。对照组运用早期程序化综合治疗。治疗组在对照组基础上实行中医分期辨证论治联合覆盖式VSD技术治疗。观察比较两组在肢体肿胀程度和疮疡积分的临床疗效以及血清肌酸激酶(CK)表达变化。结果治疗后治疗组肢体肿胀程度、疮疡积分较对照组明显降低和减少(P<0.05)。治疗后治疗组CK表达量明显低于对照组(P<0.05)。结论中医分期辨证论治联合覆盖式VSD技术治疗舟山眼镜蛇咬伤临床疗效显著,能有效控制肿胀与疮疡的发生与发展,同时明显降低CK表达量。

Objective:To investigate the clinical efficacy of the combination of traditional Chinese medicine syndrome differentiation and staged treatment with coverage-style vacuum sealing drainage(VSD)technology in the treatment in early-stage swelling,ulceration,and serum creatine kinase(CK)expression in patients with Naja atra bite.Methods:A total of 120 patients who met the inclusion criteria were randomly divided into a treatment group and a control group,with 60 patients in each group.The control group received early procedural comprehensive treatment,while the treatment group received the combination of traditional Chinese medicine syndrome differentiation and staged treatment with coverage-style VSD technology on the basis of the control group.The clinical efficacy of the two groups in terms of limb swelling degree and ulcer score,as well as changes in serum CK expression,were observed and compared.Results:The comparison of limb swelling degree and ulcer score between the two groups before treatment showed no statistical significance.After treatment,the limb swelling degree and ulcer score in the treatment group were significantly lower than those in the control group,with statistical difference between the two groups(P<0.05).After treatment,the CK expression level in the treatment group was significantly lower than that in the control group,with statistical difference between the two groups(P<0.05).Conclusion:The combination of traditional Chinese medicine syndrome differentiation and staged treatment with coverage-style VSD technology is effective in controlling the occurrence and development of swelling and ulceration in patients with Naja atra bite,as well as significantly reducing CK expression levels.This treatment method is worthy of clinical promotion.