多模态MRI定量评估骨骼肌的研究进展

Research progress in quantitative assessment by multimodal MRI in skeletal muscle

骨骼肌是骨骼-肌肉系统的重要组成部分,其解剖结构存在差异,病理生理状态的改变对于运动及骨骼肌疾病的治疗、预后都具有重要意义。概述骨骼肌形态学和组织学MRI定量参数(如骨骼肌横截面积、脂肪含量、炎性水肿状态、肌纤维结构类型)的评估方法及其临床应用,以及骨骼肌健康或疾病状态与MRI定量参数的相关性。就多模态MRI定量评估骨骼肌结构及功能的研究进展予以综述,并对其临床应用前景进行展望。

Skeletal muscle,as an important component of the skeletal-muscular system,exhibits unique anatomical and structural characteristics.Pathophysiological changes in skeletal muscle are critical to movement,treatment approaches,and prognosis of skeletal muscle diseases.This review provides an overview of MRI-based quantitative parameters used to assess skeletal muscle morphology and histology(such as cross-sectional area,fat content,inflammatory edema status,and muscle fiber structure types),their assessment methods,and clinical applications,as well as the correlation between skeletal muscle health or disease states and MRI-derived quantitative parameters.Additionally,the review highlights recent advances in multimodal MRI for the quantitative evaluation of skeletal muscle structure and function,offering insights into potential clinical applications.