双相情感障碍患者稳定期残留症状与其家庭及社会功能的关系

Correlation between residual symptoms and family and social function in patients with bipolar affective disorder

目的 分析双相情感障碍患者稳定期残留症状与其家庭及社会功能的相关性。方法选择2021年1月~2023年6月在我院进行治疗的150例双相情感障碍患者作为研究对象。依据治疗12周后患者的社会功能缺陷筛选量表(Social Disability Screening Schedule,SDSS)评分结果,将其分为家庭及社会功能缺陷组(n=47)、无家庭及社会功能缺陷组(n=103),比较两组基线资料及治疗后抑郁、躁狂症状残留情况。采用相关性分析双相情感障碍患者稳定期残留症状与家庭及社会功能的相关性。结果 家庭及社会功能缺陷组存在睡眠障碍史、治疗期间发作≥3次、文化程度为初中及以下、杨氏躁狂量表(Young Manic Rating Scale,YMRS)10~20分、汉密尔顿抑郁量表(Hamilton Depression Scale,HAMD)8~21分占比高于无家庭及社会功能缺陷组(P<0.05);多因素Logistic回归分析显示存在睡眠障碍史、文化程度为初中及以下、YMRS评分10~20分、HAMD评分8~21分均为引发双相情感障碍患者稳定期家庭及社会功能缺陷的影响因素(P<0.05);相关性分析显示,双相情感障碍患者稳定期患者YMRS评分、HAMD评分与SDSS评分呈正相关(P<0.05)。结论 双相情感障碍患者稳定期患者家庭及社会功能缺陷发生可能性较高,残留症状、睡眠障碍史、治疗期间发作次数较多、文化程度均为引发家庭及社会功能缺陷的危险因素。

Objective Analysis of patients with bipolar affective disorder plateau residual symptoms and family and social function of correlation.Methods Choose from January 2021 to June 2023 in our hospital for treatment of 150patients with bipolar affective disorder as the research object.According to the Social Disability Screening Scale(SDSS)scores after 12 weeks of treatment,the patients were divided into family and social dysfunction group(n=47)and no family and social dysfunction group(n=103).The baseline data and residual symptoms of depression and mania after treatment were compared between the two groups.Using correlation analysis plateau residual symptoms of patients with bipolar affective disorder,family and social function of correlation.Results Compared with the non-family and social dysfunction group,the family and social dysfunction group had a history of sleep disorders,≥ 3 episodes during treatment,education level of junior high school or below,Young manic rating scale(YMRS)10~20 points,and Hamilton Depression Scale(HAMD)8~21 points(P<0.05).Multivariate Logistic regression analysis showed that history of sleep disorders,education level of junior high school or below,YMRS score of 10~20 points,HAMD score of 8~21points were the influencing factors of family and social dysfunction in patients with bipolar affective disorder(P<0.05).Correlation analysis showed that YMRS score and HAMD score were positively correlated with SDSS score in patients with stable bipolar affective disorder(P<0.05).Conclusion Patients with stable bipolar affective disorder are more likely to have family and social dysfunction.Residual symptoms,history of sleep disorders,more seizures during treatment,and education level are risk factors for family and social dysfunction.