甲状腺癌手术患者抑郁风险与疾病感知、希望水平的相关性分析

Correlation analysis between depression risk,disease perception,and hope level in patients undergoing thyroid cancer surgery

目的 分析甲状腺癌手术患者抑郁风险与疾病感知、希望水平的相关性。方法 选择2022年1月~2022年12月在我院进行甲状腺癌手术治疗的246例患者作为研究对象。采用汉密顿抑郁量表(Hamilton Depression Scale,HAMD)评估患者抑郁程度并进行分组,抑郁组(n=106)、无抑郁组(n=140)。收集患者基线资料、简易疾病感知问卷(brief illness perception questionnaire,BIPQ)、中文版Herth希望量表(Herth Hope Index,HHI)评分,采用多因素Logistic回归分析影响甲状腺癌手术患者抑郁发生的因素,采用Pearson相关性分析甲状腺癌手术患者抑郁与疾病感知、希望水平的相关性。结果 抑郁组BIPQ评分≥35分,HHI评分≤23分的例数占比高于无抑郁组(P<0.05);多因素Logistic回归分析显示BIPQ评分≥35分,HHI评分≤23分均为影响甲状腺癌手术患者抑郁的危险因素(P<0.05);相关性分析显示,甲状腺癌手术患者HAMD评分与BIPQ评分呈正相关,与HHI评分呈负相关(P<0.05)。结论 疾病负性感知高、希望水平低均可能引起甲状腺癌手术患者抑郁情绪,临床可通过提高患者疾病感知及希望水平,降低抑郁风险及程度。

Objective Analyze the correlation between depression risk,disease perception,and hope level in patients undergoing thyroid cancer surgery.Methods A total of 246 patients who underwent surgical treatment for thyroid cancer in our hospital from January 2022 to December 2022 were selected as the study objects.Hamilton Depression Scale(HAMD)was used to assess the degree of depression of the patients and they were divided into two groups:depression group(n=106)and no depression group(n=140).Baseline data,brief illness perception questionnaire(BIPQ)and Chinese version of Herth hope index(HHI)were collected.Multivariate Logistic regression was used to analyze the factors affecting the occurrence of depression in patients undergoing thyroid cancer surgery,and Pearson correlation was used to analyze the correlation between depression and disease perception and hope level in patients undergoing thyroid cancer surgery.Results The proportion of BIPQ score ≥35 points and HHI score ≤ 23 points in depressed group was higher than that in non-depressed group(P<0.05).Multivariate Logistic regression analysis showed that BIPQ score ≥ 35 and HHI score ≤ 23 were risk factors for depression in patients undergoing thyroid cancer surgery(P<0.05).Correlation analysis showed that HAMD score was positively correlated with BIPQ score and negatively correlated with HHI score in patients undergoing thyroid cancer surgery(P<0.05).Conclusion Both high disease negative awareness and low hope level may cause depression in patients undergoing thyroid cancer surgery.The risk and degree of depression can be reduced by improving patients' disease perception and hope level.