焦虑抑郁情绪对前列腺增生患者症状的影响

The influence of anxiety and depression on symptoms of patients with prostate hyperplasia

目的 探讨焦虑抑郁情绪对前列腺增生相关症状的影响。方法 纳入2021年3月~2023年3月我院84例前列腺增生患者,采用汉密顿焦虑、抑郁量表(Hamilton Anxiety Scale,Hamilton Depression Scale,HAMA、HAMD)评估焦虑、抑郁情绪,将是否合并焦虑或(和)抑郁设为焦虑抑郁组以及非焦虑抑郁组。比较两组患者国际前列腺症状评分(International prostate symptom score,IPSS)、膀胱过度活动症评分表(Overactive bladder syndrome score,OABSS),检测两组患者最大尿流率(Maximum flowrate,Qmax)、膀胱残余尿量(Residual urine volume of bladder,RUV)等尿流动力学指标。结果 84例前列腺增生患者合并焦虑抑郁30例,其中焦虑10例,抑郁6例,焦虑合并抑郁14例;焦虑抑郁组IPSS评分、OABSS评分均显著高于非焦虑抑郁组(P<0.05);焦虑抑郁组Qmax显著低于非焦虑抑郁组,RUV显著高于非焦虑抑郁组(P<0.05)。结论 前列腺增生患者容易出现焦虑抑郁情绪,并且焦虑抑郁情绪可能会加重下尿路症状以及尿流动力学紊乱。

Objective To explore the impact of anxiety and depression on symptoms related to prostate hyperplasia.Methods Eighty-four patients with benign prostatic hyperplasia in our hospital from March 2021 to March 2023were selected as the study subjects.The Hamilton Anxiety Scale and Hamilton Depression Scale(HAMA and HAMD)were used to assess anxiety and depression emotions.They were set as the anxiety depression group and non anxiety depression group based on whether anxiety or(and)depression.The International Prostate Symptom Score(IPSS)and Overactive Bladder Syndrome Score(OABSS)between two groups of patients were compared.The urodynamic indicators such as maximum flow rate(Qmax)and residual urine volume of bladder(RUV)in two groups of patients were detected.Results 84 patients with benign prostatic hyperplasia complicated with anxiety and depression in 30 cases,including 10 cases of anxiety,6 cases of depression,and 14 cases of anxiety combined with depression;The IPSS score and OABSS score of the anxiety and depression group were significantly higher than those of the non anxiety and depression group(P<0.05).The Qmax of the anxiety and depression group was significantly lower than that of the non anxiety and depression group,and the RUV was significantly higher than that of the non anxiety and depression group(P<0.05).Conclusion Patients with benign prostatic hyperplasia are prone to anxiety and depression,which may exacerbate lower urinary tract symptoms and urodynamic disorders.