我国百草枯中毒研究的文献计量和可视化分析

Bibliometric and visual analysis of domestic research on paraquat poisoning

目的通过可视化软件归纳国内百草枯中毒研究领域的发展脉络和热点,为今后研究提供建议和参考。方法检索1949—2023年中国知网(CNKI)数据库中有关百草枯中毒的相关文献进行计量分析,并运用CiteSpace软件(6.2.R6)对作者、机构、关键词等模块绘制可视化知识图谱。结果本研究共纳入1099篇文献。首篇文献发表于1977年,发文量高峰出现在2014年。主要发文机构为高校及其附属医院,机构间合作较少。发文量≥3篇的核心作者共49位,部分核心作者合作密切。《中华劳动卫生职业病杂志》等10种期刊是文献的主要来源。关键词聚类分析发现研究热点主题为临床表现(肺损伤、肺纤维化、帕金森病)、治疗(血液灌流)和预后,关键词突现分析显示近年来“敌草快”和“代谢组学”是研究前沿。82.9%的文献至少被引用过1次,52.3%的文献获得基金项目资助。结论我国百草枯中毒研究围绕致病机制和治疗取得了一些成果,未来需加强研究机构间合作,加大研究深度。

Objective To explore the development trends,hotspots in the field of paraquat poisoning research,and to provide references for future research.Methods Literature on paraquat poisoning from the CNKI database from 1949 to 2023 was retrieved,then quantitative analysis was conducted and CiteSpace software(6.2.R6)was used to draw a visual knowledge graph of authors,institutions,and keywords.Results A total of 1099 articles were included,and the study begun in 1977,the number of publications reached its peak in 2014.The main publishing institutions were universities and their affiliated hospitals,with less cooperation between institutions.There were a total of 49 core authors who had published 3 or more articles,with some of them collaborating closely.The Chinese Journal of Industrial Hygene and Occupational Diseases and other 10 journals were the main sources of literature.Keyword clustering analysis found that the hot topics of research are clinical manifestations(lung injury,pulmonary fibrosis,Parkinson's disease),treatment(hemoperfusion),and prognosis.Keyword emergence analysis showed that“diquat”and“metabolomics”have been at the forefront of research in recent years.Eighty-two point nine percent of the literature had been cited at least once,and 52.3%of the literature had received funding from funding projects.Conclusion In the field of research on paraquat poisoning in China,some achievements have been made in the mechanisms of poisoning and treatment.In the future,it is necessary to strengthen cooperation between research institutions and further increase research depth.