面向农产品兽药抗生素残留检测的HPLC-MS优化研究

Optimization of HPLC-MS for Detection of Antibiotic Residues in Agricultural Products and Veterinary Drugs

随着食品安全要求的提高,农产品中抗生素残留检测成为保障公众健康的重要环节。HPLC-MS技术凭借高灵敏度和多组分同步的检测能力,已成为残留检测的核心工具。本文通过对色谱分离、质谱检测参数及样品前处理进行优化,实现了检测性能的提升,验证了检测方法的灵敏度、稳定性和质量控制策略,确保结果的准确性与一致性。并结合实际案例分析展示了优化方案的应用效果,以期为农产品兽药残留检测提供一定的技术参考。

With the improvement of food safety requirements,the detection of antibiotic residues in agricultural products has become an important link to protect public health.HPLC-MS technology has become the core tool for residue detection due to its high sensitivity and multi-component synchronization.In this paper,by optimizing chromatographic separation,mass spectrometry detection parameters and sample pretreatment,the detection performance was improved,and the sensitivity,stability and quality control strategy of the detection method were verified to ensure the accuracy and consistency of the results.Combined with the actual case analysis,the application effect of the optimization scheme was demonstrated,in order to provide a certain technical reference for the detection of veterinary drug residues in agricultural products.