布地奈德雾化吸入联合阿奇霉素治疗小儿支气管炎的临床分析

Clinical Observation of Budesonide Nebulized Inhalation Combined with Azithromycin in the Treatment of Pediatric Bronchitis

目的分析小儿支气管炎应用布地奈德雾化吸入联合阿奇霉素治疗的临床效果。方法非随机选取靖江市中医院于2023年8—12月收治的63例小儿支气管炎患儿为研究对象,根据治疗方式分为单独用布地奈德组(n=20),单独用阿奇霉素组(n=20),联合用药组(n=23),比较3组患儿的炎症指标、总有效率。结果联合用药组白细胞计数、C蛋白反应低于其他单独用药组,差异有统计学意义(P均<0.05)。单独使用布地奈德组的总有效率为40.00%(8/20),单独使用阿奇霉素组的总有效率为60.00%(12/20),联合用药组的总有效率为91.30%(21/23),联合组总有效率高于单独用药组,差异有统计学意义(χ^(2)=12.824,P<0.05)。结论布地奈德雾化吸入联合阿奇霉素治疗小儿支气管炎的临床效果显著,可降低炎症反应,提高治疗效果。

Objective To analyze the clinical effect of budesonide inhalation combined with azithromycin in the treat⁃ment of bronchitis in children.Methods Sixty-three children with bronchitis admitted to Jingjiang Hospital of Tradi⁃tional Chinese Medicine from August to December 2023 were non-randomly selected as the study subjects.According to the treatment methods,they were divided into budesonide group alone(n=20),azithromycin group alone(n=20)and combined treatment group(n=23).The inflammatory indexes and total effective rate of the three groups were com⁃pared.Results The WBC count and C protein response in the combined treatment group were lower than those in the other groups,and the differences were statistically significant(all P<0.05).The total effective rate of budesonide alone group was 40.00%(8/20),that of azithromycin alone group was 60.00%(12/20),and that of combination group was 91.30%(21/23).The total effective rate of combination group was higher than that of alone group,and the difference was statistically significant(χ^(2)=12.824,P<0.05).Conclusion Budesonide aerosol inhalation combined with azithromy⁃cin in the treatment of pediatric bronchitis has significant clinical effect,which can reduce the inflammatory response and improve the therapeutic effect.