传统手术与射频消融术治疗原发性肝癌术后肝内复发的临床价值研究

Clinical Value of Traditional Surgery and Radiofrequency Ablation in the Treatment of Intrahepatic Recurrence after Primary Liver Cancer

目的探讨传统手术和射频消融术治疗原发性肝癌术后肝内复发的临床效果。方法非随机选取2020年11月—2023年10月贵州省人民医院肝胆外科收治的570例原发性肝癌术后肝内复发患者为研究对象,按治疗方法分为对照组(n=300,采取传统手术)与研究组(n=270,采取射频消融术)。比较两组手术相关指标、肝功能指标、并发症发生率、6个月生存率。结果研究组手术时间、术中出血量、住院天数均优于对照组,差异有统计学意义(P均<0.05)。治疗后,两组肝功能指标均较治疗前降低,差异有统计学意义(P均<0.05)。研究组并发症发生率为1.85%(5/270),低于对照组的5.67%(17/300),差异有统计学意义(χ^(2)=5.573,P<0.05)。研究组患者6个月生存率高于对照组,差异有统计学意义(P<0.05)。结论原发性肝癌术后肝内复发患者采取射频消融术治疗可降低并发症发生率,缩短手术时间及术后恢复时间,提高患者的生存率。

Objective To investigate the clinical effect of conventional surgery and radiofrequency ablation in the treatment of postoperative intrahepatic recurrence of primary hepatocellular carcinoma.Methods A total of 570 pa⁃tients with postoperative intrahepatic recurrence of primary hepatocellular carcinoma admitted to the Department of Hepatobiliary Surgery of Guizhou Provincial People's Hospital from November 2020 to October 2023 were nonrandomly selected as study subjects.They were divided into the control group(n=300,adopting traditional surgery)and the study group(n=270,adopting radiofrequency ablation)according to treatment methods.Surgery-related in⁃dexes,liver function indexes,complication rates,and 6-month survival rates were compared between the two groups.Results The operation time,intraoperative bleeding and hospitalisation days of the study group were better than those of the control group,and the differences were statistically significant(all P<0.05).After treatment,the liver function indexes of both groups were lower than those before treatment,and the difference was statistically significant(all P<0.05).The complication rate of the study group was 1.85%(5/270),which was lower than that of the control group,which was 5.67%(17/300),and the difference was statistically significant(χ^(2)=5.573,P<0.05).The 6-month survival rate of patients in the study group was higher than that of the control group,and the difference was statistically signifi⁃cant(P<0.05).Conclusion Radiofrequency ablation for patients with postoperative intrahepatic recurrence of primary hepatocellular carcinoma can reduce the complication rate,shorten the operation time and postoperative recovery time,and improve the survival rate of patients.