庆大霉素联合地塞米松明胶海绵在防治干槽症中的临床效果观察

Application of Gentamicin Combined with Dexamethasone Gelatin Sponge in Patients with Mandibular Impacted Wisdom Tooth Extraction and its Prevention and Treatment Effect on Dry Socket

目的探究庆大霉素联合地塞米松明胶海绵在防治干槽症中的临床效果观察。方法非随机选取2020年3月—2024年3月中山市东升医院收治的80例经下颌阻生智齿拔除手术患者为研究对象,根据治疗方法不同分为观察组和对照组,每组40例。对照组在牙拔除后牙槽窝内植入地塞米松明胶海绵,观察组植入庆大霉素联合地塞米松明胶海绵,比较两组患者患者牙齿恢复情况、术后疼痛情况及术后干槽症及其他并发症发生情况。结果术后第3、5、7天,两组的疼痛评分均低于术后第1天,且观察组评分低于对照组,差异有统计学意义(P均<0.05)。与植入前比较,两组牙槽窝愈合指数上升、牙龈指数下降,且观察组创口愈合时间较对照组更短,观察组整体恢复情况优于对照组,差异有统计学意义(P均<0.05)。观察组干槽症的发生率为10.00%(4/40),低于对照组的27.50%(11/40),差异有统计学意义(χ^(2)=4.021,P<0.05)。结论庆大霉素联合地塞米松明胶海绵能有效降低患者的疼痛程度,加快牙齿恢复进程,能有效降低干槽症的发生率。

Objective To explore the clinical effect of gentamicin combined with dexamethasone gelatin sponge in pre⁃vention and treatment of dry trough.Methods A total of eighty patients with mandibular impacted wisdom tooth extrac⁃tion treated in Dongsheng Hospital of Zhongshan City from March 2020 to March 2024 were non-randomly selected as the study objects,and divided into observation group and control group according to different treatment methods,with forty cases in each group.The control group was implanted with dexamethasone gelatin sponge in the alveolar cavity after tooth extraction,and the observation group was implanted with gentamicin combined with dexamethasone gelatin sponge.The tooth recovery,postoperative pain,postoperative dry socket and other complications were compared be⁃tween the two groups.Results On the 3rd,5th and 7th day after surgery,the pain scores of both groups were lower than those of the 1st day after surgery,and the scores of the observation group were lower than those of the control group,and the differences were statistically significant(all P<0.05).Compared with before implantation,alveolar heal⁃ing index increased and gingival index decreased in the two groups,and the wound healing time in the observation group was shorter than that in the control group,and the overall recovery in the observation group was better than that in the control group,the differences were statistically significant(all P<0.05).The incidence of dry groove in the obser⁃vation group was 10.00%(4/40),lower than 27.50%(11/40)in the control group,the difference was statistically signifi⁃cant(χ^(2)=4.021,P<0.05).Conclusion Gentamicin combined with dexamethasone gelatin sponge can effectively reduce the pain degree of patients, accelerate the process of tooth recovery, and effectively reduce the incidence of dry slot.