1例多发性骨髓瘤患者发生晕厥的病例分析与干预

Analysis of the cause of syncope in a case of multiple myeloma and its intervention

本文报道1例多发性骨髓瘤患者在药物治疗后发生晕厥的病例。临床药师通过查阅相关文献,对晕厥原因进行详细分析,并对晕厥与所用药物的关联性进行了评价。结果表明,患者的晕厥可能与使用来那度胺和硼替佐米有关。调整治疗方案为伊沙佐米联合地塞米松后,患者未再出现晕厥。临床药师参与该病例的诊治,体现了临床药师在肿瘤多学科诊疗团队中药物方案制定、不良反应防控方面具有积极作用。

The article reports a patient with multiple myeloma who experienced syncope after drug treatment.The clinical pharmacist conducted a detailed analysis of the causes of the syncope by reviewing relevant literature,and evaluated the relationship between the syncope and the drugs used.The results showed that the patient's syncope might be related to the use of lenalidomide and bortezomib.After adjusting the treatment plan to ixazomib combined with dexamethasone,the patient did not experience syncope again.The involvement of the clinical pharmacist in the diagnosis and treatment of this case demonstrates the positive role of clinical pharmacists in multidisciplinary oncology teams,particularly in drug regimen formulation and adverse reaction prevention.