肺癌MUSE-DWI与ss-EPI DWI成像质量的对比研究

Comparative study of imaging quality between MUSE-DWI and ss-EPI DWI in lung cancer

目的:探讨多重灵敏度编码扩散加权成像(MUSE-DWI)与常规扩散加权成像(ss-EPI DWI)在肺癌成像质量的对比。方法:连续性收集44例于扬州大学附属医院行胸部磁共振检查的肺癌患者,获取患者ss-EPI DWI和MUSE-DWI图像。由两名观察者分别对两种DWI序列的图像质量进行主观视觉定性评估,评估指标包括病灶辨识度、图像伪影、形变程度及整体图像质量;客观评估方面,计算并比较信噪比(SNR)、对比噪声比(CNR)、表观扩散系数(ADC)及最大横纵经。结果:MUSE-DWI序列在病灶辨识度、图像伪影、形变程度及整体图像质量方面优于传统ss-EPI DWI,差异有统计学意义(P<0.001)。MUSE-DWI序列显示肺癌病灶的SNR、CNR高于ss-EPI DWI,差异有统计学意义(P<0.001,P<0.05),两组间扫描肺癌的最大纵径差异有统计学意义(P<0.001),两组间病灶ADC值及病灶最大横径差异无统计学意义。结论:与常规单次激发平面回波扩散加权成像相比,MUSE-MRI可以提升肺癌图像质量,减少肺部DWI图像中的伪影和几何形变,提高病灶的SNR和CNR,在不影响ADC值测量的情况下提高解剖细节及病灶边界的清晰度。

Objective:To compare the imaging quality of multi-sensitivity encoding diffusion-weighted imaging(MUSE-DWI)and single-shot echo planar imaging diffusion-weighted imaging(ss-EPI DWI)in lung cancer.Methods:A total of 44 patients with lung cancer who underwent chest magnetic resonance imaging in the Affiliated Hospital of Yangzhou University were continuously collected.Ss-EPI DWI and MUSE-DWI images were obtained,and two observers performed subjective visual qualitative assessment of the image quality of the two DWI sequences,The evaluation indicators included lesion identification,image artifacts,degree of deformation and overall image quality.In terms of objective evaluation,signal-to-noise ratio(SNR),contrast-to-noise ratio(CNR),apparent diffusion coefficient(ADC),maximum transverse and longitudinal diameters were calculated and compared.Results:In terms of subjective evaluation:MUSE-DWI sequence was superior to traditional ss-EPI DWI in lesion identification,image artifacts,deformation degree and overall image quality,and the differences were statistically significant(P<0.001).For objective evaluation:MUSE-DWI sequence showed higher SNR and CNR of lung cancer lesions than those of ss-EPI DWI,and the differences were statistically significant(P<0.001,P<0.05).There were statistically significant differences in the maximum longitudinal diameter of lung cancer between the two groups(P<0.001).There was no significant difference in ADC value and maximum transverse diameter of lesions between the two groups.Conclusion:Compared with conventional single-shot planar echo diffusion-weighted imaging,MUSE-MRI can improve the image quality of lung cancer,reduce artifacts and geometric deformation in lung DWI images,improve the SNR and CNR of lesions,and improve the clarity of anatomical details and lesion boundaries without affecting ADC value measurement.