个性化钛网联合浓缩生长因子修复前牙槽嵴缺损的临床疗效

Clinical eficacy of customized titanium mesh combined with concentrated growth factors for restoration of anterior alveolar ridge defects

目的:探究个性化钛网联合浓缩生长因子修复前牙槽嵴缺损的临床疗效。方法:纳入105例前牙槽嵴缺损患者作为研究对象,均行种植修复。根据随机数字表法分为研究组(52例)和对照组(53例),对照组采用个性化钛网覆盖,研究组在对照组基础上联合浓缩生长因子。随访1年,分析2组种植成功率、牙槽嵴高度、骨增量、牙槽骨骨密度、骨厚度、美学效果及并发症情况。结果:术后1年,2组研究对象中发生种植体松动或脱落例数均为0,种植成功率100%。研究组牙槽嵴的高度、骨增量、牙槽骨骨密度、骨厚度均大于对照组(P<0.05)。研究组红色美学指数与白色美学指数评分高于对照组(P<0.05)。研究组出现术后肿痛、牙周感染各2例,牙龈出血、过敏各1例,对照组出现术后肿痛、牙龈出血、过敏各1例,牙周感染2例(P>0.05)。结论:个性化钛网联合浓缩生长因子修复前牙槽嵴缺损能改善牙槽嵴高度及骨代谢,提升美学效果。

Objective:To observe the clinical efficacy of customized titanium mesh combined with concentrated growth factors(CGF)for restoration of anterior alveolar ridge defects.Methods:105 patients with anterior alveolar ridge defects were included and underwent implant restoration.The patients were classified into 2 groups by random number table method,those in control group(n=53)received customized titanium mesh,in study group(n=52)received customized titanium mesh combined with CGF.After 1 year follow-up,the success rate of implantation,alveolar ridge height,alveolar ridge bone augmentation,alveolar bone mineral density,bone thickness,aesthetic results and complications were compared between the 2 groups.Results:In 1-year follow-up,no implant loosening and shedding occurred in the 2 groups,and the success rate of implantation was 100%.The height of the alveolar ridge,the horizontal bone augmentation,the alveolar bone mineral density and bone thickness of study group were greater than those of the control group(P<0.05).Study group scored higher on pink aesthetic/white aesthetic score(PES/WES)than control group(P<0.05).In study group,there were 2 cases of postoperative swelling and pain,2 cases of periodontal infection,1 case of gingival bleeding and 1 of allergy.In control group,there was 1 case of postoperative swelling,1 of pain,1 of gingival bleeding,1 of allergy and 2 of periodontal infection(P>0.05).Conclusion:Application of customized titanium mesh combined with CGF for restoration of anterior alveolar ridge defects can improve the height of the alveolar ridge and bone metabolism,ensure the aesthetic results.