摘要
艾司氯胺酮作为氯胺酮的异构体,与消旋体氯胺酮相比,其应用剂量更小,具有较强的镇痛和镇静作用。艾司氯胺酮在心血管和精神方面不良反应小,代谢快、体内清除率高,对呼吸循环影响轻微,在产科麻醉方面有显著的效果。
As an isomer of ketamine,esketamine has smaller application dose,stronger analgesic and sedative effects compared with racemic ketamine.Esketamine has advantages such as few adverse reactions in cardiovascular and mental aspects,rapid metabolism and high clearance rate in the body,and slight impact on respiratory circulation,so it shows a significant effect in obstetric anesthesia.
作者
王璐
阎文军
WANG Lu;YAN Wenjun(the First Clinical Medical College of Lanzhou University,Lanzhou,Gansu,730000;Department of Anesthesiology,Gansu Provincial People′s Hospital,Lanzhou,Gansu,730000)
出处
《实用临床医药杂志》
CAS
2024年第20期128-132,共5页
Journal of Clinical Medicine in Practice
基金
国家自然科学基金项目(81860233)
甘肃省自然科学基金项目(21JR7RA621)
甘肃省科技计划项目(21JR7RA675)。
关键词
艾司氯胺酮
产科
静脉
全身麻醉
术后镇痛
esketamine
Department of Obstetrics
veins
general anesthesia
postoperative analgesia
