推拿治疗失眠的神经-内分泌-免疫网络机制探讨

Exploration on neuro-endocrine-immune network mechanism of tuina therapy for insomnia

失眠与神经-内分泌-免疫(NEI)网络存在多环节的相互作用,集中在神经递质、细胞活性因子以及下丘脑-垂体-肾上腺轴、褪黑素等方面。睡眠-觉醒的调节针对的是各系统中所有出现异常活动的物质,绝非单一系统的某一物质,推拿治疗失眠是整体的又是双向的,具有自限性调节和质量调节的特点,与NEI网络理论有较高的一致性。文章概述推拿治疗失眠与NEI网络的相关性,探讨推拿对失眠NEI网络调控的影响,为失眠的推拿疗法提供更多理论支持和科学依据。

Insomnia and neuro-endocrine-immune(NEI)network have multi-link interactions,focusing on neurotransmitters,cellular active factors,and the hypothalamic-pituitary-adrenal axis,melatonin,and so on.The regulation of sleep-wakefulness targets all the substances in each system that show abnormal activity,never a single substance in a single system.Tuina therapy for insomnia is holistic and bidirectional,with self-limiting regulation and qualitative regulation,which is in high agreement with the theory of neuro-endocrine-immune network.This paper outlines the correlation between tuina therapy for insomnia and the NEI network,and explores the influence of tuina on the regulation of the NEI network of insomnia,in order to provide more theoretical support and scientific basis for tuina therapy for insomnia.