认知行为治疗对提高复发性抑郁障碍患者服药依从性的影响

Effect of cognitive behavioral therapy on improving medication compliance in patients with recurrent depressive disorder

目的探讨认知行为治疗对提高复发性抑郁障碍患者服药依从性的影响。方法选取2020年1月至2022年6月吉安市第三人民医院收治的80例复发性抑郁障碍患者作为研究对象,按照随机数字表法分为观察组与对照组,每组40例。对照组给予文拉法辛治疗,观察组在对照组的基础上联合认知行为治疗。比较两组汉密尔顿抑郁量表(Hamilton depression scale,HAMD)评分、汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA)评分、自尊量表(self-esteem scale,SES)评分、生命质量测定量表评分及服药依从性。结果治疗后,两组HAMD、HAMA评分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。治疗后,两组SES评分均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。治疗后,两组社会、心理、生理、信仰、环境、独立性评分均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。观察组服药依从性高于对照组,差异有统计学意义(P<0.05)。结论认知行为治疗复发性抑郁障碍患者效果显著,可显著缓解患者抑郁情绪与焦虑情绪,提高患者自尊水平、生命质量及服药依从性,值得借鉴。

Objective To explore the effect of cognitive behavioral therapy on improving medication compliance in patients with recurrent depressive disorder.Methods 80 patients with recurrent depressive disorder who were treated in the Ji'an Third People's Hospital from January 2020 to June 2022 were selected as the research subjects,they were divided into the observation group and the control group according to the random number table method,with 40 cases in each group.The control group was treated with venlafaxine,and the observation group was treated with cognitive behavioral therapy on the basis of the control group.The Hamilton depression scale(HAMD)score,Hamilton anxiety scale(HAMA)score,self-esteem scale(SES)score,quality of life score and medication compliance were compared between the two groups.Results After treatment,the scores of HAMD and HAMA of the two groups were lower than those before treatment,and the observation group was lower than the control group,the differences were statistically significant(P<0.05).After treatment,the SES scores of the two groups were higher than those before treatment,and the observation group was higher than the control group,the differences were statistically significant(P<0.05).After treatment,the scores of social,psychological,physiological,belief,environment and independence of the two groups were higher than those before treatment,and the observation group was higher than the control group,the differences were statistically significant(P<0.05).The medication compliance in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The effect of cognitive behavioral therapy on patients with recurrent depressive disorder is significant,which can significantly alleviate the depression and anxiety of patients,improve the self-esteem level,quality of life and medication compliance of patients,and is worthy of extensive reference.