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引导组织再生术联合牙周植骨术治疗牙周-牙髓联合病变患者的效果

Effects of guided tissue regeneration combined with periodontal bone grafting in treatment of patients with combined periodontal-endodontic lesions
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摘要 目的:观察引导组织再生术联合牙周植骨术治疗牙周-牙髓联合病变患者的效果。方法:选取2021年5月至2023年8月该院收治的66例牙周-牙髓联合病变患者进行前瞻性研究,按照随机数字表法将其分为对照组和观察组各33例。对照组采用牙周植骨术治疗,研究组在对照组基础上联合引导组织再生术治疗,比较两组治疗前后牙齿松动度、牙周健康指数[牙龈退缩度(GR)、临床附着丧失(CAL)、牙周袋深度(PD)]、咀嚼功能(咬合力、咀嚼效率)、炎性因子[白细胞介素-6(IL-6)、C反应蛋白(CRP)、肿瘤坏死因子-ɑ(TNF-ɑ)]水平,以及并发症发生率。结果:治疗后,两组患牙松动度低于治疗前,但组间比较,差异无统计学意义(P>0.05);两组GR、CAL、PD水平均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05);两组咀嚼效率、咬合力均高于治疗前,且研究组高于对照组,差异有统计学意义(P<0.05);两组IL-6、CRP、TNF-ɑ水平均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05);两组并发症发生率比较,差异无统计学意义(P>0.05)。结论:引导组织再生术联合牙周植骨术治疗牙周-牙髓联合病变患者,可减轻牙齿松动度和牙周炎症反应,改善牙周健康,提高咀嚼功能,效果优于单纯牙周植骨术治疗。 Objective:To observe effects of guided tissue regeneration combined with periodontal bone grafting in treatment of patients with combined periodontal-endodontic lesions.Methods:A prospective study was conducted on 66 patients with combined periodontal-endodontic lesion admitted to this hospital from May 2021 to August 2023.According to the random number table method,they were divided into control group and observation group,33 cases in each group.The control group was treated with periodontal bone grafting,while the study group was combined with guided tissue regeneration on the basis of that of the control group.The tooth mobility,the levels of periodontal health index[gingival recession(GR),clinical attachment loss(CAL),periodontal pocket depth(PD)],masticatory function(bite force,masticatory efficiency)and inflammatory factors[interleukin-6(IL-6),C-reactive protein(CRP),tumor necrosis factor-ɑ(TNF-ɑ)]levels before and after the treatment,and the incidence of complications were compared between the two groups.Results:After the treatment,the tooth mobility levels of the two groups were lower than those before the treatment,but there was no significant difference between the two groups(P>0.05).The levels of GR,CAL and PD of the two groups were lower than those before the treatment,and those in the study group were lower than those in the control group;and the differences were statistically significant(P<0.05).The masticatory efficiency and the bite force of the two groups were higher than those before the treatment,those in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).The levels of IL-6,CRP and TNF-ɑin the two groups were lower than those before the treatment,those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of complications between the two groups(P>0.05).Conclusions:Guided tissue regeneration combined with periodontal bone grafting in the treatment of the patients with combined periodontal-endodontic lesions can reduce the tooth mobility and the periodontal inflammatory response,improve the periodontal health,and improve the masticatory function.Moreover,it is superior to simple periodontal bone grafting.
作者 黄龙 HUANG Long(Department of Stomatology of Wanzai County People’s Hospital,Yichun 336100 Jiangxi,China)
出处 《中国民康医学》 2024年第22期42-45,共4页 Medical Journal of Chinese People’s Health
关键词 牙周-牙髓联合病变 引导组织再生术 牙周植骨术 牙齿松动度 咀嚼功能 牙周健康指数 炎性因子 Combined periodontal-endodontic lesion Guided tissue regeneration Periodontal bone grafting Tooth mobility Masticatory function Periodontal health index Inflammatory factor
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