基于Pd/ZnS纳米复合材料的无酶葡萄糖生物传感器的研究

Research on nonenzymatic glucose biosensor based on Pd/ZnS nanocomposite

葡萄糖检测在食品、医药、化工、纺织、印染、能源等诸多领域具有重要意义。文章以乙酸锌、硫化钠和氯化钯为原料,聚乙二醇作为控制材料形貌的表面活性剂,抗坏血酸作为还原剂,在超声条件下合成Pd/ZnS纳米复合材料,采用场发射扫描电镜(FESEM)和X射线能谱仪(EDS)等方法对合成的纳米复合材料进行表征,基于Pd/ZnS纳米复合材料修饰的玻碳电极(GCE)构建无酶葡萄糖传感器,采用循环伏安法(CV)研究葡萄糖的电化学行为,采用电流-时间(i-t)曲线法研究传感器的性能,包括检测电位和催化剂的量,并探索检测葡萄糖的最佳实验条件。在最佳实验条件下,葡萄糖的线性范围为0.763 4~35.710 0 mmol/L,检测限为0.139 9 mmol/L(S/N=3)。

The detection of glucose is of great significance in many fields such as food,medicine,chemical industry,spinning and weaving,printing and dyeing,and energy.The article uses zinc acetate,sodium sulfide and palladium chloride as raw materials,polyethylene glycol as a surfactant to control the morphology of the material,and ascorbic acid as a reducing agent to synthesize Pd/ZnS nanocomposites under ultrasound conditions.The synthesized nanocomposites are characterized using methods such as field emission scanning electron microscope(FESEM)and energy dispersive X-ray spectroscopy(EDS).The nonenzymatic glucose sensor is constructed based on Pd/ZnS nanocomposite modified glassy carbon electrode(GCE).The cyclic voltammetry(CV)is studied the electrochemical behavior of glucose.The performance of the sensor,including detection potential and catalyst amount,is studied using the current time(i-t)curve method,and the optimal experimental conditions for detecting glucose are explored.Under the optimal experimental conditions,the linear range of glucose is 0.7634-35.7100 mmol/L,and the detection limit is 0.1399 mmol/L(S/N=3).