摘要
Time is brain.How fast an occluded cerebral artery can be reopened is directly related to how many brain cells can be saved.The iden-tification of a tissue window as indicated by the presence of a penumbra on multimodality imaging study has opened the time window of treatment to 24 hours after the onset.1 From 2019 to 2022,the issue of direct intra-arterial(IA)mechanical thrombectomy(MT)is non-inferior to bridging therapy or not has been settled.2 Bridging therapy may have slight advantage in re-opening the occluded arteries than direct IA MT.3 Recently published data on IA MT to treat acute ischaemic stroke(AIS)from a large vessel occlusion but with a low Alberta Stroke Programme Early CT(ASPECT)score indicated that in these patients,performing a multimodality imaging study may not be necessary.Multimodality imaging study including MRI of head,MRA of head and neck and magnetic resonance perfusion(MRP)of head or CT of head,CTA of head and neck and CT perfusion(CTP)of head are must-to do tests when evaluating patients with AIS with an onset time between 6 and 24 hours in current clinical practice.